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Product Line: Pharmaceutical Chemicals

4′,4”(5”)-Di-tert-butyldicyclohexano-18-crown-6

CAS 223719-29-7

Molecular structure of 4′,4”(5”)-Di-tert-butyldicyclohexano-18-crown-6

CAS · 223719-29-7

01

Product Overview

4′,4”(5”)-Di-tert-butyldicyclohexano-18-crown-6 is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Colorless to pale yellow liquid or off-white semi-solid
Purity: 90.0% min
03

Applications

4',4''(5'')-Di-tert-butyldicyclohexano-18-crown-6 is a highly specialized crown ether widely used in chemical synthesis, separation processes, and catalysis. Crown ethers are known for their ability to selectively complex with metal cations, and this particular derivative, with bulky tert-butyl and dicyclohexano substituents, exhibits enhanced selectivity and solubility in organic solvents. It finds applications as a phase-transfer catalyst in organic reactions, facilitating the transfer of ionic species between aqueous and organic phases to improve reaction efficiency. In analytical chemistry, it is used for selective extraction, separation, and detection of alkali and alkaline earth metal ions. Additionally, it serves as a stabilizing ligand for organometallic complexes and as a component in supramolecular chemistry, where its rigid and sterically hindered structure enables the design of molecular recognition systems, ion sensors, and selective ion transport materials.

04

Benefits

The benefits of 4',4''(5'')-Di-tert-butyldicyclohexano-18-crown-6 arise from its high cation-binding affinity, steric protection, and solubility in organic media. The crown ether cavity, modified with bulky tert-butyl and dicyclohexano groups, enhances selectivity for specific metal ions while reducing undesired side interactions, making it ideal for precision catalysis and ion separation. Its chemical and thermal stability ensures consistent performance under demanding reaction conditions. The hydrophobic substituents improve solubility in nonpolar organic solvents, expanding its applicability in organic synthesis and phase-transfer catalysis. Furthermore, its structural rigidity and functional versatility make it a valuable tool in supramolecular chemistry, allowing chemists to design systems for selective ion recognition, transport, and sensor applications with high efficiency and reproducibility.

05

Conclusion

4',4''(5'')-Di-tert-butyldicyclohexano-18-crown-6 is a high-performance crown ether that offers exceptional selectivity, stability, and versatility in chemical synthesis, catalysis, and analytical applications. Its unique structural modifications enhance metal ion recognition and solubility, making it indispensable for precision chemistry, phase-transfer reactions, and supramolecular systems. By enabling efficient ion complexation and controlled chemical processes, this compound continues to support innovation in both research and industrial applications.

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