4-(trifluoromethoxy)-Benzeneacetic acid ethyl ester
CAS 1206550-93-7
CAS · 1206550-93-7
Product Overview
4-(trifluoromethoxy)-Benzeneacetic acid ethyl ester is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Light yellow to yellow liquid |
|---|---|
| Purity (HPLC) | 98% min |
| Water | 1.0% max |
Applications
4-(Trifluoromethoxy)-Benzeneacetic acid ethyl ester (CAS 1206550-93-7) is a fluorinated aromatic ester widely used in pharmaceutical, agrochemical, and chemical synthesis. Its trifluoromethoxy group imparts strong electron-withdrawing properties and lipophilicity, making it a valuable intermediate in the development of bioactive compounds such as anti-inflammatory, anticancer, and antiviral agents. It is frequently employed in the synthesis of heterocyclic scaffolds, amides, and esters, enabling medicinal chemists to fine-tune pharmacokinetic and pharmacodynamic properties of drug candidates. Additionally, it serves as a building block in agrochemical synthesis for the preparation of herbicides and fungicides, as well as in specialty chemical research for fluorinated material development.
Benefits
The benefits of 4-(trifluoromethoxy)-Benzeneacetic acid ethyl ester derive from its fluorinated functionality and reactive ester group. The trifluoromethoxy substituent enhances chemical stability, metabolic resistance, and lipophilicity of downstream molecules, improving drug-like properties. The ethyl ester group enables easy transformations, such as hydrolysis to the corresponding carboxylic acid or amidation, providing synthetic flexibility. The compound is chemically stable, soluble in common organic solvents, and compatible with a variety of reaction conditions, which facilitates multi-step synthesis. Its combination of electronic modulation and reactive functionality makes it highly useful for medicinal chemistry and materials science applications.
Conclusion
4-(Trifluoromethoxy)-Benzeneacetic acid ethyl ester is a versatile fluorinated intermediate used extensively in pharmaceuticals, agrochemicals, and specialty chemical synthesis. Its trifluoromethoxy group and ester functionality provide both chemical stability and synthetic flexibility, enabling the design of bioactive compounds with improved properties. By supporting selective transformations and enhancing molecular performance, this compound continues to play an important role in modern drug discovery and chemical development.
Previous
Phthaloyl Amlodipine丨CAS 88150-62-3
Next