CAS · 4334-88-7
Product Overview
4-Ethoxycarbonylphenylboronic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White solid |
|---|---|
| Purity (HPLC): | 98% min |
| Assay (HPLC): | 98% min |
| 4-Carboxyphenylboronic acid (HPLC): | 0.5% max |
| Unknown single impurity (HPLC): | 0.15% max |
Applications
4-Ethoxycarbonylphenylboronic acid is an important organoboron compound widely used in organic synthesis, pharmaceutical research, and material science. It serves as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the construction of biaryl and heteroaryl compounds, which are essential scaffolds in drug discovery, agrochemical development, and fine chemical synthesis. The ethoxycarbonyl group offers additional reactivity, allowing further functionalization such as hydrolysis, amide formation, or ester transformations. This compound is also utilized in the synthesis of fluorescent dyes, ligands, and functional materials where boronic acid groups facilitate molecular assembly, sensing applications, or binding interactions with diols and sugars.
Benefits
The compound provides significant advantages due to its high reactivity, stability, and functional versatility. The boronic acid moiety enables efficient and selective formation of carbon–carbon bonds under mild conditions, while the ethoxycarbonyl substituent allows for diverse chemical transformations and fine-tuning of molecular properties. Its crystalline nature and good shelf stability ensure ease of handling, storage, and reproducibility in multi-step syntheses. Additionally, the compound is compatible with a variety of catalysts, solvents, and reaction conditions, allowing high yields and scalability. These characteristics make it a valuable building block in both research and industrial applications.
Conclusion
4-Ethoxycarbonylphenylboronic acid is a versatile organoboron intermediate essential for the synthesis of biaryl structures, bioactive molecules, and functional materials. Its reactivity in cross-coupling reactions, combined with the chemical flexibility of the ethoxycarbonyl group, makes it indispensable in pharmaceuticals, agrochemicals, and advanced materials research. The compound continues to support innovation in chemical synthesis, medicinal chemistry, and material design.
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