CAS · 115619-01-7
Product Overview
4-(4-Ethylpiperazin-1-ly)aniline is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Characteristics: | Yellow or gray to black solid |
|---|---|
| Purity: | 98% min |
| Single impurity: | 0.5% max |
| Water content: | 1% max |
Applications
4-(4-Ethylpiperazin-1-yl)aniline is mainly used as an intermediate in pharmaceutical synthesis, especially in the preparation of compounds containing piperazine scaffolds, which are common in antihistamines, antipsychotics, antidepressants, and anticancer agents. It serves as a key structural fragment in the synthesis of kinase inhibitors, receptor modulators, and enzyme blockers. In chemical research, it is employed to design heterocyclic compounds and functionalized aromatic systems for bioactive molecule development. The compound is also utilized in polymer and dye chemistry, where its amine groups can participate in condensation or coupling reactions, enabling the formation of functional polymers, pigments, and advanced coatings.
Benefits
The benefits of 4-(4-Ethylpiperazin-1-yl)aniline lie in its chemical reactivity, structural adaptability, and dual-functionality. The presence of both aromatic and aliphatic amine groups allows for diverse chemical transformations, including acylation, alkylation, and coupling reactions. Its piperazine ring enhances biological compatibility and drug-like properties when incorporated into pharmaceutical molecules, improving solubility, metabolic stability, and receptor binding affinity. The compound's stability under standard storage conditions, along with its solubility in common organic solvents, makes it convenient for large-scale chemical processes. Its versatility also enables researchers to design and modify molecules for a broad spectrum of chemical and biological applications.
Conclusion
In summary, 4-(4-Ethylpiperazin-1-yl)aniline is a multifunctional organic compound widely used as a synthetic intermediate in pharmaceutical, chemical, and material research. Its dual amine functionality, structural flexibility, and high reactivity make it an ideal building block for producing complex molecules and advanced materials. With its balance of stability, reactivity, and synthetic utility, it plays a valuable role in modern drug discovery and chemical innovation.
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