(3S,4S)-3-Amino-4-hydroxy-tetrahydropyran

(3S,4S)-3-Amino-4-hydroxy-tetrahydropyran is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

(3S,4S)-3-Amino-4-hydroxy-tetrahydropyran is primarily used as a chiral building block in pharmaceutical and fine chemical synthesis. Its stereochemically defined tetrahydropyran ring makes it valuable for constructing complex molecules, particularly those requiring precise three-dimensional orientation for biological activity. The compound is applied in the synthesis of active pharmaceutical ingredients, intermediates, and analogs where heterocyclic frameworks and multiple functional groups are essential. In research settings, it is used to explore structure–activity relationships, develop stereoselective synthetic methodologies, and design molecules with improved binding affinity and selectivity. It is also employed in medicinal chemistry programs focused on carbohydrate mimetics and bioisosteric replacements.

The compound offers several advantages due to its defined stereochemistry and multifunctional nature. The presence of both amino and hydroxyl groups enables diverse chemical transformations, including acylation, alkylation, and cyclization, supporting flexible synthetic strategies. Its rigid yet functional tetrahydropyran scaffold enhances control over molecular conformation, which is critical in drug design and biological evaluation. The stereochemical purity of the compound ensures predictable reactivity and consistent performance in synthesis, reducing the need for additional resolution steps. Additionally, its compatibility with standard organic solvents and reaction conditions facilitates efficient handling in laboratory and development environments.

(3S,4S)-3-Amino-4-hydroxy-tetrahydropyran is a valuable chiral intermediate for pharmaceutical research and complex molecule synthesis. Its applications in medicinal chemistry and stereoselective synthesis, combined with benefits such as multifunctionality, defined stereochemistry, and synthetic versatility, make it an important building block for developing biologically relevant and structurally sophisticated compounds.

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