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Product Line: Pharmaceutical Chemicals

(3S)-(+)-3-Fluoropyrrolidine hydrochloride

CAS 136725-53-6

Molecular structure of (3S)-(+)-3-Fluoropyrrolidine hydrochloride

CAS · 136725-53-6

01

Product Overview

(3S)-(+)-3-Fluoropyrrolidine hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Off-white or light pink solid
Purity (GC): 98% min
Purity (HPLC): 99% min
HNMR: Confirms the structure
03

Applications

 

 

1. Pharmaceutical Intermediate

Used as a chiral building block for the synthesis of enantiomerically pure pharmaceuticals.

The fluorine atom and stereochemistry influence biological activity, metabolic stability, and lipophilicity of drug candidates.

Key intermediate in developing drugs targeting the central nervous system (CNS), antiviral, and anti-inflammatory agents.

2. Medicinal Chemistry Research

Valuable for structure-activity relationship (SAR) studies involving fluorinated heterocycles.

Enables exploration of fluorine's effect on pharmacokinetics and receptor binding.

3. Fluorinated Compound Synthesis

Serves as a precursor for synthesizing fluorinated analogs of natural products and bioactive molecules.

Supports the development of novel fluorinated ligands and catalysts.

04

Benefits

Chirality and Purity: Provides access to single enantiomer compounds, important for drug efficacy and safety.

Improved Drug Properties: Fluorine substitution often enhances metabolic stability, membrane permeability, and binding affinity.

Versatile Intermediate: Useful in diverse chemical transformations due to its functional groups and stereochemistry.

Water Soluble: Facilitates ease of handling and formulation in aqueous environments.

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Conclusion

(3S)-(+)-3-Fluoropyrrolidine hydrochloride (CAS 136725-53-6) is a crucial chiral fluorinated intermediate widely used in pharmaceutical synthesis and medicinal chemistry. Its stereochemistry and fluorine substitution offer enhanced drug-like properties, making it valuable for developing new therapeutics. The compound's versatility and enantiomeric purity continue to drive its importance in drug discovery and development.

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