CAS · 3350-78-5
Product Overview
3,3-Dimethylacryloyl chloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Colorless to light yellow liquid |
|---|---|
| Assay (GC): | 98% min |
| Impurities: | 2.0% max |
| Refractive index (n20/D): | 1.476 |
Applications
1. Pharmaceutical Intermediates
Used as a building block in the synthesis of active pharmaceutical ingredients (APIs).
Introduces the 3,3-dimethylacryloyl group, which may modify biological activity or solubility of drug molecules.
2. Agrochemical Synthesis
Employed in the preparation of herbicides, fungicides, and pesticides, where the dimethyl group enhances lipophilicity and metabolic stability.
3. Polymer and Resin Chemistry
Serves as a functional monomer modifier in specialty acrylic resins, copolymers, and crosslinking agents.
Enhances mechanical and chemical resistance of final polymer materials.
4. Chemical Research and Development
Utilized in organic synthesis to introduce bulky, reactive groups into complex molecules.
Often used in structure-activity relationship (SAR) studies for medicinal and material chemistry.
Benefits
Versatile Functional Group: Acyl chlorides are excellent intermediates for creating esters, amides, and anhydrides.
Steric Bulk from Dimethyl Groups: The two methyl groups at the 3-position provide steric hindrance, which can influence reaction selectivity or stability.
Reactive Yet Selective: Allows controlled acylation under mild conditions, useful in multi-step syntheses.
Conclusion
3,3-Dimethylacryloyl chloride (CAS 3350-78-5) is a valuable synthetic intermediate used in pharmaceuticals, agrochemicals, and polymers. Its reactivity and steric properties make it ideal for tailoring the function and performance of target molecules. As industries continue to explore novel functional materials, this compound remains an important building block in fine chemical synthesis.
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