CAS · 54060-30-9
Product Overview
3-Aminophenylacetylene is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Light yellow to yellow liquid |
|---|---|
| Assay (HPLC) | 99.0% min |
| 3-Amino phenyl ethylene | 0.1% max. |
| Any other substances | 0.2% max. |
| Residue on ignition | 0.1% max. |
| Water | 0.2% max. |
Applications
3-Aminophenylacetylene is primarily used in organic synthesis, pharmaceutical research, and materials science as a versatile intermediate. In medicinal chemistry, it serves as a building block for the synthesis of bioactive compounds, heterocyclic molecules, and kinase inhibitors. Its amino and alkyne functionalities allow for selective reactions, including click chemistry, Sonogashira coupling, and cycloaddition reactions, enabling the construction of complex molecular architectures. The compound is also applied in polymer and materials research for preparing functionalized polymers, conjugated materials, and electronic or optical devices. Additionally, it is used in research to study alkyne reactivity, amino group transformations, and novel synthetic methodologies in both academic and industrial contexts.
Benefits
3-Aminophenylacetylene offers several advantages that make it valuable in chemical and pharmaceutical applications. The combination of an amino group and a terminal alkyne provides dual reactivity, allowing for diverse functionalization strategies and efficient multi-step synthesis. Its well-defined aromatic structure ensures chemical stability and predictable reactivity under a variety of conditions. The compound is highly versatile for coupling reactions, enabling rapid construction of libraries of derivatives for drug discovery and materials development. Additionally, its compatibility with modern synthetic techniques, such as click chemistry and cross-coupling reactions, facilitates streamlined and reproducible synthetic workflows.
Conclusion
3-Aminophenylacetylene is a versatile intermediate used in pharmaceuticals, organic synthesis, and materials science. Its dual-functional amino and alkyne groups, combined with structural stability, make it an effective building block for constructing complex bioactive molecules and functional materials. Overall, 3-Aminophenylacetylene supports efficient synthesis, structural diversification, and innovation in research and industrial applications.
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