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Product Line: Pharmaceutical Chemicals

2-Mercapto-1,3,4-thiadiazol

CAS 18686-82-3

Molecular structure of 2-Mercapto-1,3,4-thiadiazol

CAS · 18686-82-3

01

Product Overview

2-Mercapto-1,3,4-thiadiazol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance White or white crystalline
Purity 98% min
Melting Point (MP) 143–146 °C
Water 0.50% max
03

Applications

2-Mercapto-1,3,4-thiadiazole (CAS 18686-82-3) is a sulfur- and nitrogen-containing heterocyclic compound widely used as an intermediate in pharmaceutical, agrochemical, and materials chemistry. In pharmaceuticals, it serves as a building block for synthesizing antibacterial, antifungal, antiviral, and anticancer agents due to the bioactive thiadiazole scaffold. In agrochemicals, it is used in the development of fungicides, herbicides, and plant-protective agents. Additionally, 2-mercapto-1,3,4-thiadiazole finds applications in polymer and material sciences, where it is employed in the preparation of corrosion inhibitors, rubber vulcanization accelerators, and metal complexing agents.

04

Benefits

The benefits of 2-mercapto-1,3,4-thiadiazole stem from its multifunctional reactivity and heterocyclic stability. The thiol group enables nucleophilic reactions, disulfide formation, and metal coordination, while the 1,3,4-thiadiazole ring provides structural rigidity, aromatic stability, and electronic effects that enhance bioactivity. Its small, versatile structure allows efficient incorporation into diverse chemical scaffolds, supporting rapid synthesis of pharmaceuticals, agrochemicals, and functional materials. Additionally, the compound's thermal and chemical stability makes it suitable for high-performance applications and long-term storage without significant degradation.

05

Conclusion

In summary, 2-mercapto-1,3,4-thiadiazole is a versatile intermediate used in pharmaceuticals, agrochemicals, and material sciences. Its applications include drug development, crop protection agents, corrosion inhibitors, and polymer additives, while its benefits lie in multifunctional reactivity, structural stability, and suitability for diverse synthetic pathways. With these properties, it continues to be an important building block for the creation of bioactive and functional chemical compounds.

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