CAS · 766-11-0
Product Overview
2-Fluoro-5-bromopyridine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless to yellow liquid |
|---|---|
| Purity (GC) | 98% min |
| Identification (GC) | Retention time of major peak in the chromatogram of the sample solution should correspond to that of standard solution as obtained in the assay |
| Moisture | 0.5% max |
| Maximum single impurity | 1.0% max |
Applications
Pharmaceutical Industry
2-Fluoro-5-bromopyridine丨766-11-0 is a key intermediate in the synthesis of various bioactive compounds, particularly in the development of pharmaceuticals. Its structure is useful for creating pyridine-based derivatives that possess antiviral, antimicrobial, and anticancer properties. It can also be utilized in the synthesis of kinase inhibitors, which are important in cancer research and drug development.
Organic Synthesis
As a halogenated pyridine derivative, 2-fluoro-5-bromopyridine is employed in organic synthesis for the creation of more complex molecules. It is used in cross-coupling reactions such as Suzuki or Heck reactions to form biaryl compounds. These compounds have broad applications in materials science and medicinal chemistry.
Material Science
The compound is used in the preparation of functionalized polymers and materials. The halogen groups (fluoro and bromo) enable the modification of polymer backbones, improving properties such as solubility, stability, and conductivity. These materials can find applications in electronics, photonics, and other high-performance industries.
Agrochemical Industry
2-Fluoro-5-bromopyridine丨766-11-0 is used in the synthesis of agrochemicals, including herbicides and pesticides. The pyridine ring is a common scaffold for developing chemicals that can effectively target specific biological pathways in plants and pests. The halogen substituents on the aromatic ring can help enhance the efficacy and selectivity of these agrochemical agents.
Chemical Research
This compound is widely utilized in chemical research for developing novel catalytic processes and reactions. It can serve as a reactive intermediate in the synthesis of various organic molecules, providing researchers with a versatile building block for more complex chemical entities.
Benefits
Versatile Building Block
The halogenated pyridine structure of 2-fluoro-5-bromopyridine makes it an ideal intermediate for creating a variety of biologically active compounds. The flexibility of the halogenated pyridine ring allows for the incorporation of other functional groups, expanding its potential in diverse chemical syntheses.
Enhanced Biological Activity
Pyridine derivatives, especially those with halogen substituents, often exhibit enhanced biological activity. The combination of fluorine and bromine atoms can help improve the binding affinity of molecules to specific biological targets, increasing the efficacy of pharmaceutical agents. This makes 2-fluoro-5-bromopyridine a valuable intermediate in drug discovery.
Improved Reactivity in Synthesis
The presence of fluorine and bromine on the pyridine ring makes 2-fluoro-5-bromopyridine more reactive in certain reactions, such as nucleophilic substitutions and cross-coupling reactions. These properties allow it to serve as a highly effective reagent in the creation of complex organic molecules, increasing the overall efficiency and yield of chemical processes.
Increased Stability of Products
Fluorine is known for its electron-withdrawing effects, which can help stabilize chemical intermediates or end products in various reactions. This increased stability can be beneficial in pharmaceuticals and materials science, where the longevity and durability of compounds are critical.
Enhanced Agrochemical Properties
The fluorine and bromine atoms in 2-fluoro-5-bromopyridine can help enhance the selectivity and potency of agrochemicals. These modifications can lead to more effective herbicides and pesticides, improving crop protection and yield without harming non-target organisms.
Conclusion
2-Fluoro-5-bromopyridine丨766-11-0 is a valuable compound with broad applications in pharmaceuticals, organic synthesis, material science, and agrochemicals. Its ability to serve as an intermediate in the synthesis of bioactive compounds, combined with its enhanced reactivity and stability, makes it a critical building block for the development of advanced chemical products. Whether in drug development, chemical research, or agrochemical applications, 2-fluoro-5-bromopyridine plays an essential role in driving innovation in these fields.
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