CAS · 41404-58-4
Product Overview
2-Bromo-5-fluoropyridine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White to slight yellow solid or liquid |
|---|---|
| Purity (HPLC/GC) | 98% min |
| Moisture (KF) | 0.50% max |
Applications
2-Bromo-5-fluoropyridine is widely used as an intermediate in pharmaceutical and agrochemical synthesis. It serves as a building block for developing biologically active compounds, including antiviral, anticancer, and anti-inflammatory agents. The compound is also employed in the synthesis of heterocyclic molecules and fluorinated derivatives, which are valuable in medicinal chemistry for improving drug properties. Additionally, it is utilized in material science for the preparation of specialty polymers and functionalized organic materials.
Benefits
The presence of both bromine and fluorine substituents in the pyridine ring enhances the compound's chemical reactivity and selectivity, enabling diverse functionalization through cross-coupling reactions. This dual halogenation improves metabolic stability and bioavailability when incorporated into drug candidates. Its versatility accelerates the synthesis of complex molecules, reducing production time and cost. The fluorine atom contributes to improved pharmacokinetic properties in medicinal applications, such as increased membrane permeability and binding affinity.
Conclusion
2-Bromo-5-fluoropyridine is a valuable synthetic intermediate offering unique reactivity and functionalization opportunities. Its dual halogen substituents enhance both chemical and biological properties of derivatives, making it a critical component in drug discovery and advanced material development. Its applications continue to expand with ongoing innovations in pharmaceutical and material sciences.
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