CAS · 14508-49-7
Product Overview
2-Chloropyrazine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Yellowish transparent liquid |
|---|---|
| Content (GC) | 98% min |
| Odour | Bitter almond flavour |
| Boiling Point | 153 to 154°C |
| Water | 3.0% max |
| Flash Point | 57°C |
Applications
2-Chloropyrazine is an important heteroaromatic compound widely used as a versatile intermediate in pharmaceutical, agrochemical, and chemical research. In pharmaceutical synthesis, it serves as a building block for the preparation of pyrazine-containing drugs, including antiviral, antibacterial, and central nervous system agents, where the pyrazine ring contributes to bioactivity and metabolic stability. In agrochemicals, 2-chloropyrazine is utilized in the synthesis of herbicides, insecticides, and fungicides, helping to incorporate the pyrazine scaffold for enhanced efficacy. Additionally, it is employed in the synthesis of fine chemicals, heterocyclic derivatives, and functionalized intermediates, providing a reactive site for nucleophilic substitution, cross-coupling, and other organic transformations in medicinal and material chemistry research.
Benefits
The benefits of 2-chloropyrazine are derived from its reactive chlorine substituent and stable pyrazine ring. The chlorine atom enables selective functionalization through substitution reactions, allowing efficient synthesis of diverse derivatives with high yield. Its heteroaromatic structure imparts stability, planarity, and favorable electronic properties, which are advantageous for drug design and agrochemical applications. 2-Chloropyrazine also supports streamlined synthetic pathways, reducing the number of reaction steps and improving process efficiency. Its versatility and compatibility with various reaction conditions make it a valuable intermediate for research and industrial production, facilitating the creation of bioactive molecules and functional materials with targeted properties.
Conclusion
In summary, 2-chloropyrazine is a versatile heteroaromatic intermediate with applications in pharmaceuticals, agrochemicals, and fine chemical synthesis. Its benefits include high reactivity, structural stability, ease of functionalization, and synthetic efficiency. By combining chemical versatility with practical utility, 2-chloropyrazine continues to be an essential compound for the development of bioactive molecules, agrochemicals, and advanced chemical intermediates.
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