CAS · 66909-30-6
Product Overview
2-Chloro-5-methylnicotinic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White or off-white solid |
|---|---|
| Purity: | 98% min |
Applications
2-Chloro-5-methylnicotinic acid is a halogenated pyridine carboxylic acid widely used in pharmaceutical research, agrochemical synthesis, and organic chemistry. It serves as a versatile intermediate for the preparation of nicotinamide derivatives, heterocyclic compounds, and biologically active molecules. In drug discovery, it is employed to synthesize anti-inflammatory agents, antimicrobial compounds, and other pharmacologically relevant derivatives where the chloro and methyl substituents help modulate electronic and steric properties. Additionally, the compound is used in agrochemical research for the development of herbicides, fungicides, and insecticides, and as a building block in fine chemical synthesis and heterocyclic chemistry.
Benefits
The compound offers several advantages due to its reactive chloro group and carboxylic acid functionality. The chlorine atom allows selective substitution in cross-coupling or nucleophilic aromatic substitution reactions, while the carboxyl group provides sites for amide or ester formation, enabling diverse chemical transformations. Its pyridine ring contributes to enhanced stability and electronic properties, which are valuable for optimizing bioactivity in drug candidates. The compound is stable under standard storage conditions, soluble in common organic solvents, and compatible with a variety of synthetic reactions, making it convenient for multi-step syntheses in both laboratory and industrial applications.
Conclusion
2-Chloro-5-methylnicotinic acid is a versatile pyridine-based intermediate essential for pharmaceuticals, agrochemicals, and heterocyclic synthesis. Its combination of halogen reactivity, carboxyl functionality, and methyl substitution allows efficient construction of bioactive molecules and fine chemicals. The compound continues to be a key building block supporting innovation in drug discovery, agrochemical development, and advanced organic synthesis.
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