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Product Line: Pharmaceutical Chemicals

2-Amino-5-chloro-2,6-difluorobenzophenone

CAS 28910-83-0

Molecular structure of 2-Amino-5-chloro-2,6-difluorobenzophenone

CAS · 28910-83-0

01

Product Overview

2-Amino-5-chloro-2,6-difluorobenzophenone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Yellow green solid
Purity: 97% min
03

Applications

2-Amino-5-chloro-2,6-difluorobenzophenone is a specialized aromatic ketone widely used as an intermediate in pharmaceutical and fine chemical synthesis. It serves as a building block in the preparation of bioactive heterocyclic compounds, including antiviral, antibacterial, and anticancer agents. Its multifunctional structure, containing amino, chloro, and fluorine substituents, allows for selective reactions in medicinal chemistry, such as nucleophilic substitution, condensation, and cross-coupling reactions. The compound is also employed in the synthesis of dyes, agrochemicals, and other functional aromatic derivatives where halogenated and amino-substituted aromatic systems are required. In research, it is used for the design and development of novel molecules with tailored electronic and steric properties, supporting structure-activity relationship studies and drug discovery programs.

04

Benefits

The compound offers several advantages due to its highly functionalized aromatic structure. The amino group provides a site for further derivatization, while the chloro and difluoro substituents enhance chemical stability, metabolic resistance, and electronic properties of downstream molecules. Its well-defined structure allows for precise and reproducible reactions in multi-step syntheses, improving yield and efficiency. The presence of fluorine atoms can enhance lipophilicity, bioavailability, and receptor-binding characteristics of derivatives, which is particularly valuable in pharmaceutical development. Additionally, the compound is stable under standard storage conditions, compatible with common solvents and reagents, and provides versatility in both laboratory-scale research and industrial-scale production.

05

Conclusion

2-Amino-5-chloro-2,6-difluorobenzophenone is a versatile and high-value intermediate for pharmaceutical, agrochemical, and fine chemical synthesis. Its multifunctional amino and halogenated aromatic structure provides chemical reactivity, stability, and flexibility, making it an essential building block for creating bioactive molecules, functional aromatic derivatives, and advanced chemical compounds. Its use supports efficient synthesis, innovation in drug discovery, and the development of high-performance materials.

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