CAS · 979-02-2
Product Overview
16-Dehydropregnenolone acetate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Fine white to almost white crystalline powder, odourless |
|---|---|
| Purity (HPLC) | 98.5% min |
| 25% solution in Methylene chloride | Almost clear solution |
| Loss on drying | 0.5% max |
| Melting point | 171–178 ℃ |
| Specific optical rotation | -38 to -39.5° |
| E1% 1cm in isopropyl alcohol at 238nm | 257–263 |
Applications
16-Dehydropregnenolone acetate is a synthetic steroid and key intermediate widely used in the pharmaceutical and chemical industries. It serves primarily as a precursor in the synthesis of corticosteroids, sex hormones, and other steroidal drugs. Due to its acetylated structure and dehydro modification, it offers a reactive platform for chemical transformations such as hydroxylation, reduction, and oxidation, enabling the preparation of a wide range of bioactive steroid derivatives. In research, it is employed as a reference compound for studying steroid biosynthesis pathways and metabolism. Its versatility in acting as a starting material for critical therapeutics makes it indispensable in hormone-related drug development.
Benefits
The benefits of 16-dehydropregnenolone acetate are rooted in its stability, functionality, and efficiency as a synthetic intermediate. Its acetylated form provides enhanced stability compared to non-acetylated analogs, making it easier to handle and store during large-scale synthesis. The compound's structure allows for regioselective and stereoselective modifications, reducing the number of synthetic steps needed to obtain target molecules. This efficiency contributes to cost-effectiveness in industrial steroid production. Additionally, its well-defined chemical profile ensures reproducibility in pharmaceutical manufacturing and research, supporting the reliable production of essential hormone-based drugs.
Conclusion
In summary, 16-dehydropregnenolone acetate is a crucial intermediate in steroid chemistry with applications in drug synthesis, biochemical research, and pharmaceutical development. Its benefits include structural stability, versatility in chemical transformations, and efficiency in producing steroidal derivatives. By providing a reliable foundation for the synthesis of vital hormones and therapeutics, this compound continues to play an important role in advancing both pharmaceutical science and industrial applications.
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