CAS · 17766-28-8
Product Overview
1-Cyclohexylpiperazine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Light yellow to colorless solid |
|---|---|
| Purity (GC): | 98% min |
Applications
1-Cyclohexylpiperazine (CAS 17766-28-8) is a heterocyclic amine widely utilized as a versatile building block in pharmaceutical, agrochemical, and chemical research. Its structure, combining a piperazine ring with a cyclohexyl group, provides both rigidity and lipophilicity, making it an attractive intermediate for designing bioactive molecules. In pharmaceuticals, it serves as a key scaffold for the synthesis of central nervous system (CNS) agents, antihistamines, antidepressants, and other therapeutic compounds. In agrochemical research, 1-cyclohexylpiperazine is used to develop pesticides and herbicides with improved bioavailability and environmental stability. Additionally, it is employed in medicinal chemistry and drug discovery programs for the preparation of derivatives that exhibit optimized pharmacokinetic and pharmacodynamic profiles.
Benefits
The benefits of 1-cyclohexylpiperazine stem from its chemical versatility and ability to modulate biological activity. Its piperazine core allows for multiple functionalization strategies, enabling the design of molecules with specific receptor interactions and improved efficacy. The cyclohexyl substituent enhances lipophilicity, aiding membrane permeability and drug absorption. In research and development, this compound facilitates rapid synthesis of structural analogs for high-throughput screening, accelerating the identification of promising therapeutic candidates. Its stability and compatibility with various chemical reactions also make it a reliable intermediate for producing high-value pharmaceutical and agrochemical products.
Conclusion
In conclusion, 1-cyclohexylpiperazine is a multifunctional intermediate that plays a crucial role in pharmaceutical, agrochemical, and chemical research. Its combination of structural versatility, stability, and bioactivity modulation makes it invaluable for the development of novel therapeutic agents and agrochemicals. By enabling efficient synthesis and optimization of bioactive molecules, it continues to support innovation in drug discovery, medicinal chemistry, and applied chemical research.
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