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Product Line: Pharmaceutical Chemicals

1-Cyanonaphthalene

CAS 86-53-3

Molecular structure of 1-Cyanonaphthalene

CAS · 86-53-3

01

Product Overview

1-Cyanonaphthalene丨CAS 86-53-3 is an aromatic compound with both naphthalene and cyano (CN) groups attached at the 1-position of the naphthalene ring. The cyano group is an electron-withdrawing substituent that significantly alters the reactivity of the aromatic ring, making it highly useful in organic synthesis and materials science.

1-Cyanonaphthalene is commonly employed in the preparation of fine chemicals, pharmaceuticals, and polymers, and is also a precursor to various naphthalene-based intermediates.

02

Product Specifications

Appearance Off-white crystalline powder
Purity (GC) 98% min
Melting Point 36–38 °C
03

Applications

1. Intermediate in Organic Synthesis

● 1-Cyanonaphthalene serves as a key intermediate in the synthesis of a variety of organic compounds.

● It is frequently used in the preparation of naphthalene derivatives, heterocyclic compounds, and other aromatic intermediates.

● Its cyano group makes it highly reactive, particularly in nucleophilic substitution reactions, enabling the synthesis of compounds such as amine derivatives.

2. Pharmaceutical and Agrochemical Synthesis

● 1-Cyanonaphthalene丨CAS 86-53-3 is a starting material for pharmaceutical compounds, especially in the synthesis of antiviral, antibacterial, and anti-inflammatory drugs.

● Its derivatives have also been studied for use in pesticides and herbicides, where the naphthalene ring system contributes to stability and bioactivity.

3. Dye and Pigment Manufacturing

● The compound can be used as a precursor in the production of naphthalene-based dyes and pigments.

● It is employed in creating brightly colored compounds for use in textiles, inks, and coatings.

4. Material Science and Polymers

● The cyano group offers opportunities for polymerization and crosslinking reactions in the production of functionalized polymers.

● 1-Cyanonaphthalene can be utilized in the synthesis of high-performance polymers for electronic applications, such as in the optical materials and conductive polymer industries.

5. Fluorescent Materials

● In organic electronics and organic light-emitting diodes (OLEDs), 1-cyanonaphthalene-based compounds show promise as components in fluorescent or phosphorescent materials.

● Its emission properties make it suitable for optical applications, particularly in developing colorants for displays and lighting.

04

Benefits

1. High Chemical Reactivity

● The cyano group significantly enhances the electrophilicity of the aromatic ring, making it highly reactive in electrophilic substitution and nucleophilic addition reactions.

● This reactivity makes it a useful building block for a wide variety of chemical syntheses.

2. Versatility in Organic Synthesis

● The compound's versatility allows it to be used in multiple synthetic routes to form aromatic amines, heterocycles, and other complex organic structures.

● It can be involved in a broad array of transformations such as hydrolysis, reduction, alkylation, and acylation.

3. Contribution to Material Science

● Functionalized naphthalene derivatives like 1-cyanonaphthalene are crucial in the development of specialty materials with desirable properties such as conductivity, optical activity, and chemical stability.

● It contributes to the development of advanced coatings, polymers, and liquid crystals used in display technologies.

4. Potential in Pharmaceuticals and Agrochemicals

● Its cyano group imparts specific bioactivity to its derivatives, making 1-cyanonaphthalene and its derivatives useful in designing pharmaceutical agents and crop protection chemicals.

● This compound is a critical component in creating drugs with antibacterial, antiviral, and anti-inflammatory properties.

05

Conclusion

1-Cyanonaphthalene丨CAS 86-53-3 is a highly valuable compound in the realms of organic synthesis, pharmaceutical chemistry, and materials science. Its cyano group endows it with high reactivity, making it an essential intermediate for the development of complex molecules, dyes, and functional materials. The pharmaceutical and agrochemical industries benefit from its derivatives in producing bioactive compounds, while the material science sector leverages its ability to contribute to the development of advanced fluorescent materials and polymers. Proper handling and storage are crucial due to its reactivity and toxicity, but its wide range of applications makes it an indispensable chemical in various fields.

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