CAS · 64013-70-3
Product Overview
Canamycin A disulfate is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade | EP11 |
|---|---|
| Characteristics | White or off white powder, odorless, hygroscopic |
| Assay (On dried basis) | 670 IU/mg min |
| Solubility | Conforms |
| Identification | 1.2.3.4 Conforms |
| Specific rotation | +103° ~ +115° |
| pH | 5.5 ~ 7.5 |
| Kanamycin B | 4.0% max |
| Sulphates | 23.0 ~ 26.0% |
| Loss on drying | 5.0% max |
| Sulphated ash | 0.5% max |
| Sterility | Conforms |
| Pyrogens | Conforms |
Applications
Canamycin A disulfate is primarily used in microbiology, pharmacological research, and antibiotic development studies. It functions as an aminoglycoside antibiotic, exhibiting inhibitory activity against a variety of Gram-positive and Gram-negative bacteria. The compound is applied in research to study bacterial protein synthesis inhibition, mechanisms of antibiotic resistance, and to evaluate antibacterial potency in vitro. It is also used as a reference or control compound in assays investigating aminoglycoside activity, helping to assess the efficacy of new antibacterial agents. Additionally, Canamycin A disulfate serves as a tool in biochemical studies of ribosomal function and translational regulation, supporting mechanistic investigations of protein synthesis inhibition and structure–activity relationships within the aminoglycoside class.
Benefits
Canamycin A disulfate provides several advantages that make it useful in research and antibiotic studies. Its well-characterized antibacterial spectrum allows reliable assessment of microbial susceptibility and resistance patterns. As a disulfate salt, it has enhanced solubility in aqueous systems, facilitating accurate dosing and reproducible experimental results. The compound's stability under standard laboratory conditions ensures consistent performance in microbiological and biochemical assays. Its activity against both Gram-positive and Gram-negative bacteria makes it a versatile reference compound for comparative studies. Additionally, its role as a tool for investigating ribosomal interactions and protein synthesis inhibition provides valuable insights into molecular mechanisms of antibiotic action and resistance, aiding in the design of novel therapeutic strategies.
Conclusion
Canamycin A disulfate is a research-grade aminoglycoside antibiotic with applications in microbiology, pharmacology, and mechanistic studies of protein synthesis. Its antibacterial activity, aqueous solubility, and stability make it a reliable tool for evaluating microbial susceptibility and understanding ribosomal function. Overall, Canamycin A disulfate is a valuable compound in antibiotic research, providing both experimental versatility and mechanistic insights for drug discovery and bacterial resistance studies.
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