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Perfluoro-1-iodohexane

CAS 355-43-1

Molecular structure of Perfluoro-1-iodohexane

CAS · 355-43-1

01

Product Overview

Perfluoro-1-iodohexane is a high-purity fluorine supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance Colorless to pale pink liquid
Purity 99% min
03

Applications

Perfluoro-1-iodohexane is a highly fluorinated organoiodine compound widely used as a reagent and intermediate in organic synthesis, materials science, and pharmaceutical research. It serves as a source of perfluoroalkyl groups, which are introduced into molecules to enhance their chemical, thermal, and oxidative stability. In pharmaceutical and medicinal chemistry, it is used for the synthesis of fluorinated drug candidates, agrochemical intermediates, and bioactive molecules, where the perfluoroalkyl chain can improve lipophilicity, metabolic stability, and membrane permeability. In materials science, it is employed in the preparation of fluorinated polymers, coatings, and surfactants, contributing to high chemical resistance, low surface energy, and thermal stability. Additionally, perfluoro-1-iodohexane participates in iodofluorination, radical, and substitution reactions, making it a versatile reagent for both laboratory-scale and industrial chemical transformations.

04

Benefits

The benefits of perfluoro-1-iodohexane arise from its unique combination of a highly stable perfluoroalkyl chain and a reactive iodine atom. This allows for efficient introduction of perfluoroalkyl groups into target molecules, enhancing chemical and thermal resistance, reducing polarity, and improving solubility in fluorinated media. In pharmaceuticals, these modifications can improve drug stability, bioavailability, and overall pharmacokinetic profiles. In materials applications, it helps produce polymers and coatings with superior hydrophobicity, non-stick properties, and long-term durability under harsh conditions. Its high reactivity in radical and substitution reactions provides chemists with precise control over molecular design, enabling the creation of advanced fluorinated compounds with tailored functional properties. Its stability and defined structure make it reliable for reproducible synthesis and large-scale applications.

05

Conclusion

Perfluoro-1-iodohexane is a valuable fluorinated intermediate with broad applications in pharmaceuticals, materials science, and organic synthesis. Its ability to efficiently introduce perfluoroalkyl groups imparts enhanced stability, lipophilicity, and chemical resistance to target molecules. The benefits of this compound-including improved drug properties, durable fluorinated materials, and versatile synthetic utility-make it a critical reagent for chemical innovation. With its reactivity, stability, and functional versatility, perfluoro-1-iodohexane continues to be an essential tool for advancing research, industrial applications, and high-performance material development.

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