CAS · 24470-78-8
Product Overview
Isopropyltriphenylphosphonium iodide is a high-purity ligands supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White or off-white solid |
|---|---|
| Related Substances | |
| Triphenylphosphine | 0.5% max |
| Triphenylphosphine oxide | 1.0% max |
| Other unknown single impurity | 0.5% max |
| Total impurities | 1.0% max |
| Purity | 99.0% min |
| Assay | 98.0% min |
| Water (K.F.) | 0.2% max |
| Solvent Residue | |
| Acetonitrile | Test result: 0.03% |
| NMR Confirmation | Consistent with chemical structure |
Applications
Isopropyltriphenylphosphonium iodide is primarily used as a phosphonium salt in the Wittig reaction, where it is converted to the corresponding ylide to form substituted alkenes from aldehydes or ketones. This allows chemists to synthesize a wide variety of olefins with controlled stereochemistry, which are important in pharmaceuticals, fine chemicals, and agrochemical intermediates. The compound also finds applications in the preparation of functionalized phosphonium salts for organocatalysis, polymer synthesis, and research on carbon–phosphorus bond reactivity. Additionally, it serves as a model reagent in academic and industrial laboratories for studying ylide formation, reaction mechanisms, and stereoselective organic transformations.
Benefits
The main benefits of isopropyltriphenylphosphonium iodide are its stability, high reactivity upon deprotonation, and solubility in common organic solvents. The isopropyl substituent provides steric control that can influence the stereochemical outcome of alkene formation, while the triphenylphosphonium core ensures predictable ylide generation. Its crystalline salt form makes it easy to handle, store, and accurately measure for reactions. The compound allows high-yield and selective transformations under mild conditions, minimizing side reactions and facilitating efficient synthesis of target molecules. Its versatility as a phosphonium reagent makes it compatible with multi-step organic syntheses, enabling the preparation of complex bioactive compounds and functional materials.
Conclusion
Isopropyltriphenylphosphonium iodide is a versatile quaternary phosphonium salt widely used in Wittig reactions and other carbon–carbon bond-forming transformations. Its stability, stereochemical influence, and high reactivity make it an essential intermediate in pharmaceutical synthesis, fine chemical production, and research laboratories. As precise olefin formation continues to be crucial in modern organic chemistry, this compound remains a valuable reagent for both academic and industrial applications.
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