Isatoic anhydride

Isatoic anhydride is a high-purity food-additives supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

1. Intermediate in Organic Synthesis

Widely used as a key intermediate in the synthesis of:

Pharmaceuticals (e.g., quinazolinone derivatives, antitumor agents)

Dyes and pigments

Agrochemicals

Reacts readily with amines to form substituted anthranilic acid derivatives and quinazolinones.

2. Synthesis of Heterocyclic Compounds

Important building block for synthesizing benzoxazinones, quinazolines, and benzimidazoles, which are core structures in many drugs and agrochemicals.

3. Pharmaceutical Chemistry

Used to prepare analgesics, anti-inflammatory agents, and antimicrobial compounds.

Enables access to bioactive molecules via ring-opening reactions.

4. Polymer and Material Science

Employed as a monomer or crosslinker in specialty polymers, especially for materials requiring thermal stability and chemical resistance.

✅ High Reactivity

The anhydride and lactam functional groups facilitate diverse chemical transformations, allowing for efficient synthesis of complex molecules.

✅ Versatility

Compatible with various nucleophiles (amines, alcohols), enabling broad application in pharmaceutical and material syntheses.

✅ Stable Yet Reactive

Stable under normal conditions but reactive enough for selective ring-opening reactions.

✅ Widely Available

Commercially available in high purity, facilitating ease of use in research and industrial settings.

Isatoic anhydride (CAS 118-48-9) is a crucial intermediate in organic synthesis, especially valuable in the pharmaceutical and agrochemical industries for constructing heterocyclic compounds and bioactive molecules. Its versatility and reactivity enable efficient synthesis of a broad range of important chemical entities, making it indispensable in medicinal chemistry and material science research.

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