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Product Line: Life Science

Bimatoprost

CAS 155206-00-1

Molecular structure of Bimatoprost

CAS · 155206-00-1

01

Product Overview

Bimatoprost is a high-purity prostaglandin supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Property Specification
Appearance White powder
Purity (HPLC) 99.0~101.0%
Identification By HPLC, IR
Solubility Very soluble in ethanol, methanol; sparingly to slightly soluble in water
Residue on Ignition 0.1% max
Heavy Metals 10 ppm max
Optical Rotation +33~+37° (C=2 in CH3OH)
Water 1.0% max
15β-Bimatoprost 0.2% max
15-Keto Derivative 0.2% max
5,6-trans Isomer 0.2% max
Any Other Impurity 0.1% max
Total Other Impurities 0.5% max
n-Hexane 0.029% max
Ethanol 0.5% max
Ether 0.5% max
Acetic Ether 0.5% max
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Applications

Bimatoprost丨CAS 155206-00-1 is a synthetic prostaglandin analog, specifically a prostamide, widely used in ophthalmology and cosmetic dermatology due to its unique ability to influence both intraocular pressure (IOP) and hair follicle growth.

1. Treatment of Glaucoma and Ocular Hypertension

● Primary medical use: Bimatoprost丨CAS 155206-00-1 is approved for reducing elevated IOP in patients with open-angle glaucoma or ocular hypertension.

● Mechanism: It enhances aqueous humor outflow through both the uveoscleral and trabecular meshwork pathways, making it one of the most potent agents in its class for IOP reduction.

2. Cosmetic Use – Eyelash Enhancement

● FDA-approved as Latisse®: Bimatoprost is used topically to increase the length, thickness, and darkness of eyelashes in individuals with hypotrichosis.

● Aesthetic dermatology: It's also being studied and used off-label for eyebrow and scalp hair growth applications.

3. Investigational Uses

● Hair regrowth: Research is ongoing into its potential for treating androgenetic alopecia (pattern hair loss), where bimatoprost shows promise due to its follicle-stimulating properties.

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Benefits

1. Superior IOP Reduction

● Bimatoprost丨CAS 155206-00-1 typically reduces IOP by 25–33%, comparable or superior to other prostaglandin analogs like latanoprost or travoprost.

● It is particularly useful in patients who are non-responsive to other glaucoma medications.

2. Dual Outflow Mechanism

● Unlike most prostaglandin analogs, bimatoprost increases aqueous humor outflow via two pathways, enhancing its efficacy.

3. Eyelash Growth Effects

● Proven efficacy in cosmetic enhancement of eyelashes, with visible results in 8–16 weeks when applied topically to the lash line.

● Encourages natural growth, not a cosmetic cover-up, and results typically persist with continued use.

4. Well-Tolerated and Convenient

● Administered once daily, improving patient adherence.

● Most side effects are localized (e.g., eye redness, darkening of eyelids or iris), with minimal systemic exposure.

5. Versatility in Formulation

● Available in both ophthalmic solution and topical cosmetic formats, addressing diverse patient needs.

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Conclusion

A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.