PIPES sesquisodium salt

PIPES sesquisodium salt is a high-purity biological-buffer supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

1. Biological Buffer

PIPES sesquisodium salt is a widely used Good's buffer, effective at maintaining stable pH in the near-neutral range.

Commonly employed in:

Cell culture media

Protein purification and enzyme assays

Molecular biology applications such as DNA/RNA isolation and electrophoresis

2. Pharmaceutical Research and Formulations

Used in the preparation of pharmaceutical buffers to stabilize pH-sensitive drugs and diagnostic reagents.

3. Electrophoresis

Suitable for PAGE and other electrophoretic methods, where precise pH control is critical.

4. Biochemical and Diagnostic Assays

Supports enzyme reactions and assays requiring pH around neutral.

1. Optimal Buffering Near Physiological pH

With a pKa of approximately 6.76, it buffers effectively close to neutral pH, important for biological systems.

2. Low Metal Ion Binding

Exhibits minimal interaction with divalent cations like Mg²⁺ and Ca²⁺, preserving enzymatic function.

3. High Water Solubility

Easily soluble, facilitating buffer preparation and consistent pH maintenance.

4. Chemical Stability

Stable under laboratory and industrial conditions, ensuring reliability.

5. Low UV Absorbance

Compatible with UV spectrophotometric measurements without interference.

PIPES sesquisodium salt (CAS 100037-69-2) is a reliable, near-neutral pH biological buffer widely used in biochemistry, molecular biology, cell culture, and pharmaceutical applications. Its buffering capacity, stability, and low interference with biological processes make it an essential reagent for precise pH control in sensitive experimental and production settings.

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