CAS · 129-46-4
Product Overview
Suramin sodium is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White powder |
|---|---|
| Purity (HPLC) | 98% min |
Applications
Suramin sodium is a polysulfonated naphthylurea derivative with broad applications in medicine and biomedical research. Clinically, it has been used as an antiparasitic agent, primarily for the treatment of African trypanosomiasis (sleeping sickness) and onchocerciasis (river blindness). In research, suramin sodium serves as an inhibitor of various enzymes and growth factor signaling pathways, including purinergic receptors, ATP-binding proteins, and G-protein-coupled signaling, making it valuable for studying cell signaling, cancer biology, and viral infections. It is also employed in experimental models to explore therapeutic strategies for neurodegenerative disorders, viral replication, and tumor progression.
Benefits
The benefits of suramin sodium stem from its broad-spectrum activity, biochemical versatility, and well-characterized pharmacological profile. Its ability to inhibit multiple enzyme systems and signaling pathways allows researchers to dissect complex biological mechanisms and test therapeutic hypotheses in vitro and in vivo. Clinically, it provides effective antiparasitic activity with long-lasting effects due to its slow elimination, reducing dosing frequency. Additionally, its water solubility and chemical stability facilitate handling and formulation in both medical and experimental settings. These properties make suramin sodium a valuable tool in drug development, biomedical research, and the study of parasitic and cellular diseases.
Conclusion
In summary, suramin sodium is a polysulfonated naphthylurea compound with applications in parasitic disease treatment, biomedical research, and cellular signaling studies. Its benefits include broad biological activity, stability, versatility in experimental design, and proven therapeutic efficacy. By combining clinical utility with research potential, suramin sodium remains an important compound in both pharmaceutical applications and scientific investigation.
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