Methyl 5-hydroxy-1-Methyl-1H-pyrazole-3-carboxylate
CAS 51985-95-6
CAS · 51985-95-6
Product Overview
Methyl 5-hydroxy-1-Methyl-1H-pyrazole-3-carboxylate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to off white solid |
|---|---|
| Purity: | 98% min |
| 1HNMR: | No obvious impurity peaks |
Applications
Methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate is primarily used as a key intermediate in pharmaceutical synthesis, particularly in the development of pyrazole-based drugs with anti-inflammatory, analgesic, or enzyme-inhibiting properties. It serves as a building block for creating more complex heterocyclic compounds and is often incorporated into reaction schemes involving condensation, acylation, or cyclization to generate novel pharmacophores. In agrochemical research, it can be utilized for the preparation of pyrazole derivatives with potential herbicidal, fungicidal, or insecticidal activity. Additionally, it finds applications in chemical research laboratories for the synthesis of functionalized pyrazole compounds used in medicinal chemistry, materials science, and organic methodology development. Its ester group allows for further modification, such as hydrolysis or transesterification, enabling the creation of diverse derivatives with tailored properties.
Benefits
The benefits of methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate lie in its versatility and functional group compatibility. Its combination of a pyrazole core, hydroxyl group, and ester functionality allows for a wide range of chemical transformations, facilitating the design of complex molecules. The compound's chemical stability and predictable reactivity make it a reliable intermediate in multi-step syntheses, supporting efficient production of target molecules. It is also valued for enhancing structural diversity in drug discovery, enabling medicinal chemists to explore new bioactive scaffolds and optimize pharmacological profiles. Its solubility in common organic solvents and compatibility with standard synthetic procedures further improve operational convenience in laboratory and industrial settings. Additionally, its use can reduce the number of synthetic steps required for certain targets, improving cost-effectiveness and yield in chemical manufacturing.
Conclusion
In summary, methyl 5-hydroxy-1-methyl-1H-pyrazole-3-carboxylate is a versatile and functional heterocyclic intermediate widely used in pharmaceutical, agrochemical, and chemical research. Its structural features, including the pyrazole ring, hydroxyl group, and ester moiety, provide excellent synthetic flexibility for the development of bioactive compounds and functional derivatives. With advantages such as chemical stability, broad reactivity, and operational convenience, it remains an important building block for innovation in drug discovery, organic synthesis, and advanced material research.
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