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Product Line: Pharmaceutical Chemicals

Hydroxyprogesterone

CAS 68-96-2

Molecular structure of Hydroxyprogesterone

CAS · 68-96-2

01

Product Overview

Hydroxyprogesterone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Almost white or pale yellow crystalline powder
Purity: 99.0% min
Loss on drying: 0.5% max
Melting point: 210°C min
Max single impurity: 0.5% max
03

Applications

 

1. Hormonal Disorder Diagnosis

Used as a biomarker in blood tests to diagnose congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency.

Monitored in newborn screening programs for early detection of adrenal disorders.

2. Pharmaceutical Intermediate

A key precursor in the synthesis of steroidal drugs, including:

Hydroxyprogesterone caproate (used to prevent preterm birth)

Corticosteroids and progestins

3. Research Applications

Studied for its role in adrenal gland function, menstrual cycle regulation, and fetal development.

Used in endocrinology and reproductive biology research.

4. Clinical Use (as Derivative)

Its derivative, hydroxyprogesterone caproate, is FDA-approved to reduce the risk of preterm delivery in women with a history of spontaneous preterm birth.

04

Benefits

✅ Diagnostic Relevance

Critical for early and accurate diagnosis of adrenal and hormonal disorders.

✅ Therapeutic Utility via Derivatives

Modified forms provide clinically proven hormonal therapy options.

✅ Biosynthetic Versatility

Serves as a building block for producing a wide range of steroidal hormones.

✅ Well-Studied Safety Profile

Has a long history of use in medical testing and drug synthesis.

05

Conclusion

Hydroxyprogesterone (CAS 68-96-2) is a biologically significant steroid hormone used extensively in medical diagnostics, pharmaceutical synthesis, and hormonal research. Its critical role in identifying adrenal disorders and producing therapeutic progestins underscores its value in both clinical and scientific fields.

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