CAS · 987-78-0
Product Overview
Citicoline is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White crystalline powder |
|---|---|
| Purity (HPLC) | 99.0% min |
| Assay | 98 – 102% min |
| Clarity and color | Colorless and clear |
| pH | 2.5 – 3.5 |
| Particle size | 100% pass 20 mesh |
| Bulk density | 0.4 – 0.5 g/cm³ |
| 5'-CMP | 1.0% max |
| Ammonium | 0.05% max |
| Free phosphoric acids | 0.01% max |
| Loss in mass on drying | 5.0% max |
| Heavy metals | 10 ppm max |
| Arsenic (As) | 2 ppm max |
| Lead (Pb) | 3 ppm max |
| Mercury (Hg) | 0.1 ppm max |
| Total plate count | 1,000 CFU/g max |
| Fungi count | 100 CFU/g max |
| Total yeast & molds | 100 CFU/g max |
| Total coliforms | 10 CFU/g max |
| Escherichia coli | Negative / 10 g |
| Salmonella species | Negative / 25 g |
| Staphylococcus aureus | Negative / g |
Applications
Citicoline, also known as CDP-choline, is a naturally occurring compound widely used in the pharmaceutical, nutraceutical, and cognitive health industries. It is primarily incorporated into dietary supplements and functional foods aimed at supporting brain health, memory, focus, and overall cognitive function. In the pharmaceutical field, citicoline is employed as a neuroprotective agent in the treatment and management of conditions such as stroke, traumatic brain injury, and neurodegenerative diseases. It is also used in research applications to study neurological pathways, neurotransmitter metabolism, and cell membrane repair. Additionally, citicoline can be formulated into capsules, tablets, powders, and liquid preparations for both clinical and consumer use.
Benefits
Citicoline offers significant advantages due to its dual role as a source of choline and cytidine. It supports the synthesis of phosphatidylcholine, a critical component of neuronal cell membranes, promoting brain cell repair and maintenance. Citicoline also enhances neurotransmitter production, particularly acetylcholine, supporting memory, learning, and attention. The compound is highly bioavailable, well-tolerated, and safe for long-term use. Its stability and solubility make it suitable for diverse formulations, ensuring consistent potency in both nutritional and therapeutic applications. Citicoline also contributes to energy metabolism in the brain, further enhancing cognitive performance and neural resilience.
Conclusion
Citicoline is a valuable compound with broad applications in cognitive health, pharmaceuticals, and nutraceuticals. Its benefits, including neuroprotection, enhanced memory and focus, support for neuronal membrane integrity, and formulation versatility, make it an essential ingredient for brain health and functional nutrition. Continued use of citicoline supports innovation in neurological therapies, cognitive supplements, and research on brain function and repair.
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