CAS · 914358-73-9
Product Overview
5-Bromo-2-methylpyridin-3-amine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Yellowish to light brown powder |
|---|---|
| Purity (HPLC): | 98.0% min |
| Identification: | HPLC |
| Moisture: | 0.5% max |
| Maximum Single Impurity: | 1.0% max |
| Melting Point: | 117–121°C |
Applications
5-Bromo-2-methylpyridin-3-amine (CAS 914358-73-9) is a heterocyclic compound widely used as an intermediate in pharmaceutical and agrochemical synthesis. Its pyridine core and amino functionality make it a valuable building block for the development of bioactive molecules, including kinase inhibitors, receptor modulators, and other therapeutic agents. It is also employed in medicinal chemistry for structure–activity relationship (SAR) studies, facilitating the design of derivatives with optimized potency, selectivity, and pharmacokinetic profiles. Additionally, it serves as a precursor for the synthesis of functionalized heterocycles, dyes, and fine chemicals.
Benefits
The benefits of 5-Bromo-2-methylpyridin-3-amine arise from its reactive amino group and halogen-substituted pyridine scaffold, which allow versatile chemical transformations such as cross-coupling, condensation, and nucleophilic substitution reactions. The bromine atom at position 5 facilitates selective functionalization, while the methyl group influences steric and electronic properties to modulate reactivity and stability. Its solubility in common organic solvents and compatibility with standard synthetic protocols make it practical for laboratory and industrial applications, supporting efficient synthesis of bioactive and functional compounds.
Conclusion
5-Bromo-2-methylpyridin-3-amine is a versatile intermediate in pharmaceutical and fine chemical synthesis. Its amino and bromopyridine functionalities enable selective derivatization and efficient synthesis of bioactive molecules and heterocyclic compounds. By supporting medicinal chemistry and industrial synthesis, it remains an important building block in chemical research and development.
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