CAS · 80-08-0
Product Overview
4,4-Diaminodiphenylsulfone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White or off-white crystal powder |
|---|---|
| Purity (HPLC) | 99% min |
| Melting point | 175℃ to 181℃ |
| Loss on drying | 0.2% max |
| Iron ion | 0.5 mg/kg max |
| Colour of solution (APHA) | 40 max |
| Foreign body (≥0.5 mm) | None |
| Foreign body (0.5 mm - 0.2 mm) | 20 max |
| Foreign body (≤0.2 mm) | 30 max |
Applications
4,4-Diaminodiphenylsulfone (CAS 80-08-0), also known as dapsone, is a well-established compound with both pharmaceutical and industrial applications. In medicine, it is widely used as an antimicrobial agent, particularly in the treatment and management of leprosy, dermatitis herpetiformis, and as part of combination therapies for malaria and certain bacterial infections. Its anti-inflammatory properties also extend its use to autoimmune skin conditions and other inflammatory diseases. In industrial chemistry, it serves as a curing agent and hardener for epoxy resins and other polymer systems, where it improves mechanical strength, thermal resistance, and chemical durability. Additionally, it is applied as an intermediate in the synthesis of dyes, pigments, and specialty chemicals.
Benefits
The benefits of 4,4-diaminodiphenylsulfone are rooted in its dual functionality as both a therapeutic agent and an industrial material. In medicine, it provides reliable antimicrobial activity, making it a cornerstone in the long-term management of leprosy and a valuable option for inflammatory skin diseases. Its broad therapeutic utility and well-studied pharmacological profile ensure safety and effectiveness when used appropriately. In industrial contexts, its ability to act as a curing agent enhances the performance of polymers, delivering improved heat stability and toughness, which are crucial for high-performance coatings, adhesives, and composites. Its versatility across disciplines underscores its enduring importance.
Conclusion
In summary, 4,4-diaminodiphenylsulfone is a multifunctional compound with significant roles in both medicine and industry. Its applications include serving as an antimicrobial and anti-inflammatory agent in pharmaceuticals, as well as a curing agent and intermediate in industrial chemistry. The benefits lie in its proven therapeutic effectiveness, structural versatility, and ability to improve material performance. This combination of biomedical and industrial value ensures that it remains an important compound for both health care and advanced materials development.
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