CAS · 40052-13-9
Product Overview
3-tert-Butoxy-3-oxopropanoic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Light yellow to yellow liquid |
|---|---|
| Purity: | 97% min |
| Water: | 1% max |
| Solvent Residue: | 2% max |
| Identification: | H-NMR; MS |
Applications
3-tert-Butoxy-3-oxopropanoic acid (CAS 40052-13-9) is a versatile organic intermediate used in pharmaceutical, agrochemical, and fine chemical synthesis. Its structure, featuring a tert-butyl ester and a keto acid functionality, makes it suitable for the preparation of heterocycles, amino acid derivatives, and other bioactive molecules. It is widely employed in medicinal chemistry for synthesizing enzyme inhibitors, prodrugs, and intermediates in drug discovery programs. Additionally, it serves as a building block for the synthesis of specialty esters, functionalized polymers, and other complex organic compounds where controlled reactivity and steric hindrance are advantageous.
Benefits
The benefits of 3-tert-butoxy-3-oxopropanoic acid arise from its dual functional groups and sterically hindered tert-butyl moiety. The keto and carboxylic acid groups allow versatile chemical transformations, including condensation, esterification, amide formation, and cyclization reactions. The tert-butyl group provides stability against premature hydrolysis and oxidation, enabling selective reactions under mild conditions. Its solubility in organic solvents and chemical stability make it practical for both laboratory and industrial-scale synthesis, while its structural versatility supports the efficient creation of bioactive and functionalized molecules.
Conclusion
3-tert-Butoxy-3-oxopropanoic acid is a valuable intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Its combination of reactive functional groups, steric protection, and chemical stability makes it ideal for constructing heterocycles, prodrugs, and specialty compounds. By enabling efficient and selective chemical transformations, it remains an important building block in modern synthetic chemistry and drug development.
Previous
3-(4-Phenoxyphenyl)-1H-pyrazolo3,4-dpyrimidin-4-amine丨CAS 330786-24-8
Next