3-(4-Phenoxyphenyl)-1H-pyrazolo3,4-dpyrimidin-4-amine
CAS 330786-24-8
CAS · 330786-24-8
Product Overview
3-(4-Phenoxyphenyl)-1H-pyrazolo3,4-dpyrimidin-4-amine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Off white to light brown powder |
|---|---|
| Purity: | 99% min |
| Identification: | The retention time of the major peak in the chromatogram corresponds to that in the chromatogram of reference standard solution |
| Related Substances: | Impurity A: 0.15% max Impurity B: 0.15% max Impurity C: 0.15% max Impurity D: 0.15% max Individual Impurities: 0.2% max Total Impurities: 1% max |
| Loss on Drying: | 1% max |
| Residue on Ignition: | 0.5% max |
| Methanol: | 0.3% max |
| Ethanol: | 0.5% max |
| Isopropanol: | 0.5% max |
| Ethyl Acetate: | 0.5% max |
| Dichloromethane: | 0.06% max |
Applications
3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 330786-24-8) is a heterocyclic compound widely used in pharmaceutical research as an intermediate and bioactive scaffold. Its fused pyrazolo-pyrimidine core, combined with the 4-phenoxyphenyl substitution, makes it a valuable building block in the development of kinase inhibitors, anticancer agents, and other therapeutic molecules targeting signal transduction pathways. The compound is applied in drug discovery programs for structure–activity relationship (SAR) studies, high-throughput screening, and the design of novel small-molecule inhibitors. Its structural framework also allows derivatization to generate libraries of analogs for optimization of potency, selectivity, and pharmacokinetic properties.
Benefits
The benefits of 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine derive from its rigid heterocyclic scaffold, which provides chemical stability and favorable interaction with biological targets. The phenoxyphenyl group enhances lipophilicity and molecular recognition, supporting strong binding affinity in enzyme or receptor systems. Its amine functionality enables further functionalization through coupling reactions, facilitating the synthesis of diverse derivatives with improved pharmacological profiles. The compound's well-defined structure and reactivity make it a versatile intermediate for medicinal chemistry, enabling efficient optimization of bioactive molecules.
Conclusion
3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a key heterocyclic intermediate with applications in drug discovery and medicinal chemistry. Its fused pyrazolo-pyrimidine core, combined with the phenoxyphenyl and amine functionalities, provides stability, reactivity, and bioactive potential. By supporting the synthesis and optimization of kinase inhibitors and other therapeutic agents, it remains an important tool in pharmaceutical research and advanced chemical development.
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