CAS · 530-36-9
Product Overview
2-Amino-1,2-diphenylethanol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | A white or slight yellow crystalline powder |
|---|---|
| Identification | Positive |
| Water | 1.0% max |
| Assay (HPLC) | 98% min |
Applications
2-Amino-1,2-diphenylethanol is a versatile chiral intermediate widely used in organic synthesis, pharmaceutical research, and asymmetric catalysis. It serves as a building block for the preparation of amino alcohol derivatives, chiral ligands, and enantioenriched compounds. In medicinal chemistry, it is applied in the synthesis of biologically active molecules, including enzyme inhibitors, antiviral agents, and central nervous system (CNS) modulators. Additionally, 2-Amino-1,2-diphenylethanol is used in asymmetric synthesis as a chiral auxiliary or catalyst precursor for enantioselective reactions, such as asymmetric reductions, epoxidations, and additions, where it helps control stereochemistry and improve reaction selectivity.
Benefits
The benefits of 2-Amino-1,2-diphenylethanol stem from its chirality, multifunctional groups, and chemical stability. The amino and hydroxyl groups provide reactive sites for derivatization, coupling, and protection, enabling flexible synthetic strategies. Its diphenyl moiety offers steric and electronic properties that enhance selectivity in asymmetric transformations. Being a stable, crystalline compound, it is easy to handle, purify, and incorporate into multi-step syntheses. Overall, it facilitates the production of enantiomerically pure compounds, improving reaction efficiency and selectivity in both laboratory and industrial settings.
Conclusion
2-Amino-1,2-diphenylethanol is a valuable chiral intermediate for asymmetric synthesis, pharmaceutical development, and fine chemical production. Its combination of chirality, reactive functional groups, and steric features enables precise control of stereochemistry and efficient construction of bioactive molecules. By supporting enantioselective transformations and versatile chemical modifications, it remains an important building block in modern organic and medicinal chemistry.
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