CAS · 9009-65-8
Product Overview
Protocatechuic aldehyde丨9009-65-8 is an organic compound with the formula C8H6O3. It is derived from protocatechuic acid, a phenolic compound found in various plants, and is typically recognized as a bioactive aldehyde. Protocatechuic aldehyde has shown potential in a variety of fields, particularly in pharmaceuticals, biotechnology, and food chemistry, due to its antioxidant and anti-inflammatory properties.
Product Specifications
| Property | Specification |
|---|---|
| Grade | EP11.0 |
| Appearance | This product is a white or almost white, and hygroscopic powder |
| Protein | 90.0% to 110.0% (anhydrous and sulfate-free substance) |
| Potency | 100 IU/mg (dried substance) min. |
| Solubility | Slightly soluble in water, almost insoluble in ethanol (96%) |
| Identification (HPLC) | The retention time of the peaks of protamine peptides A, B, C, and D in the sample should be identical to the standard solution. A: 13%-18%, B: 21%-28%, C: 31%-38%, D: 19%-24% |
| Identification (Potency Assay) | Positive reaction in potency assay |
| Identification (Sulfates) | Yields the reactions characteristic of sulfates |
| Clarity and Color of the Solution | The solution is not more opalescent than reference suspension II and not more intensely colored than reference solution BY6 or Y6 |
| Absorbance | Maximum 0.1 between wavelengths of 260 nm and 280 nm |
| Related Substances | Total impurities shall be not more than 8.0%, reporting limit: 0.5% |
| Sulfates (dried substance) | 16% to 24% |
| Iron | 10 ppm max |
| Loss on Drying | 5.0% max |
| Bacterial Endotoxin | 6.0 EU/mg max |
| Microbial Limit | The total count of aerobic bacteria, molds, and yeasts shall not exceed 100 cfu/g |
Applications
1. Pharmaceutical and Medical Applications
● Antioxidant Properties:
Protocatechuic aldehyde has potent antioxidant activity, helping to scavenge free radicals and reduce oxidative stress, which is crucial in preventing chronic diseases such as cancer, cardiovascular diseases, and neurodegenerative disorders.
● Anti-inflammatory Effects:
It exhibits anti-inflammatory activity, which makes it potentially beneficial in treating conditions such as arthritis and other inflammatory disorders.
● Antibacterial and Antifungal Properties:
Protocatechuic aldehyde has been shown to have antibacterial and antifungal effects, making it a potential candidate for developing antimicrobial agents.
● Potential in Cancer Treatment:
Studies suggest that protocatechuic aldehyde may have anticancer properties, possibly inhibiting the growth of cancer cells and inducing apoptosis (programmed cell death) in cancerous cells.
2. Food and Beverage Industry
● Natural Antioxidant:
As a naturally occurring phenolic compound, it can be used as a natural preservative in food products to prevent oxidation, enhance shelf-life, and maintain the quality of food.
● Flavoring Agent:
Protocatechuic aldehyde is sometimes used as a flavor compound in food and beverages due to its pleasant, mildly bitter taste. It may also add complexity to the flavor profile of certain beverages, especially tea and fruit-based products.
3. Cosmetic and Skincare Industry
● Anti-aging and Skin Protection:
Due to its antioxidant properties, protocatechuic aldehyde is used in the development of anti-aging skincare products, helping to protect the skin from free radical damage and environmental stressors.
● Skin Healing:
The compound has also been shown to promote skin regeneration and may help in the treatment of wound healing and skin inflammation.
4. Biochemical and Industrial Applications
● Research in Enzyme Inhibition:
Protocatechuic aldehyde is studied for its enzyme inhibition properties, particularly in inhibiting oxidative enzymes like lipoxygenases, which are involved in inflammatory responses.
● Synthesis of Bioactive Compounds:
It serves as a precursor or intermediate in the synthesis of various bioactive compounds in pharmaceutical and biotechnology research.
Benefits
1. Powerful Antioxidant
● Acts as a free radical scavenger, reducing oxidative stress and potentially preventing cellular damage, which is associated with aging and chronic diseases.
2. Anti-inflammatory
● Helps to reduce inflammation in the body, potentially aiding in the treatment of inflammatory conditions such as arthritis and inflammatory bowel disease (IBD).
3. Antimicrobial
● Demonstrates antibacterial and antifungal properties, making it effective against a variety of pathogens, which could support the development of natural antimicrobials.
4. Promising in Cancer Research
● Shows potential as an anticancer agent, possibly helping to inhibit the growth of tumor cells and support cancer prevention and treatment.
5. Versatile in Cosmetic Applications
● Provides protection against skin aging and supports wound healing, making it a valuable ingredient in cosmetic products.
Conclusion
Protocatechuic aldehyde丨9009-65-8 is a bioactive compound with a wide range of health benefits and applications in pharmaceuticals, food preservation, cosmetics, and biotechnology. Its antioxidant, anti-inflammatory, antimicrobial, and anticancer properties make it a promising compound for further research and development. As a naturally occurring compound, it holds significant potential in natural product-based therapies and wellness formulations.
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