CAS · 108-73-6
Product Overview
Phloroglucinol is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade: | EP10.0 |
|---|---|
| Characters: | White or almost white powder |
| Identification (IR, TLC): | IR conforms to the CRS (2.2.24); the principal spot in the chromatogram obtained with the test solution is similar in position and size to the reference solution (2.2.27) |
| Loss on drying: | 0.5% max |
| Appearance of solution: | Clear and not more intensely colored than reference solution BY5 |
| pH: | 4.0 - 6.0 |
| Any impurities: | 0.1% max |
| Total impurities: | 0.3% max |
| Heavy metals: | 0.002% max |
| Chlorides: | 0.02% max |
| Sulphates: | 0.05% max |
| Sulphated ash: | 0.1% max |
| Assay: | 99% - 101% |
Applications
1. Pharmaceutical Industry
A. Antispasmodic Agent
● Therapeutic Use: Used as a smooth muscle relaxant to relieve spasms in the gastrointestinal, urinary, and biliary tracts.
● Brand Examples: Found in drugs like Spasfon®, often combined with other active ingredients.
● Conditions Treated: Functional bowel disorders (e.g., irritable bowel syndrome), dysmenorrhea, renal or biliary colic, and painful bladder syndrome.
B. Analgesic and Anti-inflammatory Potential
● Exhibits mild analgesic and anti-inflammatory properties, especially in combination formulations.
● Investigated for its synergistic effects with other drugs in pain management.
2. Chemical and Analytical Applications
A. Reagent for Lignin and Pentose Detection
● Phloroglucinol-HCl Test: A classical colorimetric test for detecting lignin in plant tissues and wood. Lignified cells stain red or pink, making it useful in botanical microscopy and wood quality assessment.
● Also used to detect pentoses and certain aldehydes in analytical chemistry.
B. Intermediate in Organic Synthesis
● Serves as a building block in the synthesis of pharmaceuticals, dyes, explosives (like TATB), and biologically active natural products.
● Its trihydroxybenzene core enables modification into a range of functional derivatives.
3. Plant Biochemistry and Natural Product Research
● Found in several natural products, including flavonoids and tannins, where it contributes to antioxidant and antimicrobial properties.
● Plays a role in plant defense mechanisms, and its derivatives are often studied for bioactivity in medicinal plants.
4. Research and Development
● Used as a precursor molecule in developing novel bioactive compounds, especially those with potential antitumor, antimicrobial, and neuroprotective effects.
● Employed in the study of polyphenol chemistry, metal chelation, and hydrogen bonding behavior due to its hydroxyl groups.
Benefits
1. Effective Smooth Muscle Relaxant
● Rapid onset and low systemic toxicity make phloroglucinol a valuable spasmolytic in both acute and chronic pain syndromes involving smooth muscles.
2. Low Toxicity and Good Tolerability
● Generally well-tolerated with minimal side effects, making it suitable for long-term or recurring use in functional disorders.
3. Versatile Chemical Reagent
● Its role in lignin detection, pentose identification, and intermediate synthesis makes it a key reagent in academic and industrial chemistry.
4. Natural Derivative with Bioactive Potential
● Its natural occurrence and compatibility with biological systems make it a promising lead compound for further pharmaceutical development.
Conclusion
Phloroglucinol丨CAS 108-73-6 is a multi-functional compound with established value in pharmaceuticals as an antispasmodic and in chemical analysis for detecting plant-derived substances. With additional roles as a synthetic intermediate, botanical stain, and natural product derivative, it continues to be a compound of interest in medical, biological, and chemical research. Its favorable safety profile and broad utility ensure its continued relevance across diverse scientific fields.
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Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.