CAS · 7085-55-4
Product Overview
Troxerutin丨7085-55-4 is a flavonoid glycoside derived from rutin, a type of flavonoid compound. It is a phenolic antioxidant known for its anti-inflammatory, antioxidant, and vascular protective properties. Troxerutin is commonly used in pharmaceuticals, cosmetics, and dietary supplements due to its beneficial effects on blood circulation and its potential to reduce swelling and inflammation.
Product Specifications
| Property | Specification |
|---|---|
| Grade | EP10 |
| Appearance | Yellowish-green, crystalline powder, hygroscopic |
| Solubility | Freely soluble in water, slightly soluble in ethanol (96%), and practically insoluble in methylene chloride |
| Identification | A) IR: The infrared spectrum should conform to the Troxerutin CRS. B) The principal peak in the chromatogram obtained with the test solution is similar in position and size to the peak in the chromatogram obtained with the reference solution. |
| Composition | - Principal peak: 80% min - Any other peak than principal peak: Each peak: 5.0% max except 1 peak can be 10.0% max |
| Ethylene Oxide (GC) | 1 ppm max |
| Loss on Drying | 5.0% max |
| Sulphated Ash | 0.4% max |
| Assay (dried substance) | 95.0% to 105.0% |
| Residual Solvents | - Methanol: 3000 ppm max |
| Total Plate Count | 1000 cfu/g max |
| Yeast & Mold | 100 cfu/g max |
| E. Coli | Negative |
| Salmonella | Negative |
Applications
1. Vascular Health and Circulation
One of the most notable uses of troxerutin is in the treatment of vascular disorders. It has been shown to improve blood circulation, especially in capillaries and microcirculatory systems, making it useful in addressing conditions related to poor circulation.
● Chronic Venous Insufficiency (CVI): Troxerutin is frequently used to treat symptoms of chronic venous insufficiency, which include swelling, varicose veins, and leg pain. It is often included in topical creams or oral supplements aimed at improving venous tone and reducing swelling and pain.
● Hemorrhoids: The anti-inflammatory and vasoprotective properties of troxerutin also make it useful in the treatment of hemorrhoids, where it can help reduce swelling, bleeding, and discomfort.
● Diabetic Retinopathy: Some studies suggest that troxerutin may also be beneficial in treating diabetic retinopathy by improving circulation in the retina and reducing oxidative stress.
2. Anti-inflammatory and Antioxidant Activity
Troxerutin丨7085-55-4 has demonstrated anti-inflammatory and antioxidant properties, making it useful in the management of inflammatory conditions.
● Reduction of Oxidative Stress: As a flavonoid, troxerutin has potent antioxidant properties that can help neutralize free radicals, thereby protecting cells and tissues from oxidative damage. This action is particularly beneficial for vascular health, as oxidative stress is a key factor in the development of various cardiovascular diseases.
● Inflammation Control: Troxerutin has been shown to inhibit pro-inflammatory cytokines and other markers of inflammation, reducing the overall inflammatory response in conditions such as arthritis and chronic inflammation.
3. Cosmetic and Dermatological Uses
Troxerutin is also utilized in cosmetic and dermatological products due to its anti-inflammatory and protective effects on the skin.
● Anti-aging: The antioxidant activity of troxerutin helps protect the skin from damage caused by free radicals, which are major contributors to skin aging. It is often included in anti-aging creams to help prevent the formation of wrinkles and fine lines.
● Skin Protection: Due to its ability to reduce inflammation and improve capillary strength, Troxerutin丨7085-55-4 is sometimes used in creams designed to treat skin redness, rosacea, or sensitive skin. It can help reduce irritation and swelling in such conditions.
● Wound Healing: Troxerutin's effects on vascular health may also promote wound healing by improving blood flow to the affected area. It may be included in topical formulations intended to treat bruises or other skin injuries.
4. Dietary Supplement
Troxerutin丨7085-55-4 is available as an ingredient in various dietary supplements, often marketed for vascular health or as a circulatory tonic.
● Support for Blood Vessels: As a supplement, troxerutin is used to support healthy circulation and to treat conditions such as varicose veins, hemorrhoids, and chronic venous insufficiency. It is believed to strengthen blood vessel walls and improve capillary function.
● Antioxidant Support: Due to its antioxidant properties, it is sometimes included in multivitamin supplements aimed at promoting overall health and protecting against oxidative stress.
Benefits
1.Improved Circulation: Troxerutin丨7085-55-4 helps strengthen blood vessels and improves circulatory health, which can be beneficial for people suffering from conditions like varicose veins, hemorrhoids, and chronic venous insufficiency.
2.Anti-inflammatory: It helps reduce inflammation and is used in treating inflammatory conditions like arthritis, muscle pain, and swelling in the veins or tissues.
3.Antioxidant: As a flavonoid, troxerutin acts as a potent antioxidant, helping to protect cells from free radical damage, which is linked to a variety of diseases, including cardiovascular diseases and age-related skin damage.
4.Skin Protection: It can improve the appearance of the skin by reducing redness, irritation, and swelling, making it a useful ingredient in skin care products designed to treat conditions like rosacea, eczema, or general skin sensitivity.
5.Vascular Health in Diabetics: It may play a role in managing complications of diabetes, particularly diabetic retinopathy, by improving microcirculation and protecting against oxidative damage in the eye.
6.Wound Healing: Troxerutin丨7085-55-4 may help with the healing of wounds, bruises, or superficial injuries by improving blood flow to the affected area, which is crucial for tissue repair.
Conclusion
Troxerutin丨7085-55-4 is a potent flavonoid glycoside with a wide range of benefits, especially for vascular health and anti-inflammatory purposes. Its primary applications include the treatment of varicose veins, hemorrhoids, and chronic venous insufficiency, along with its use as an antioxidant and anti-inflammatory agent in dietary supplements and skincare products. With its antioxidant, anti-inflammatory, and vascular protective properties, troxerutin is a valuable ingredient in both pharmaceuticals and cosmetics. However, like any active ingredient, it should be used responsibly, particularly when it comes to drug interactions and side effects.
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