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Molecular structure of Tropine

CAS · 120-29-6

01

Product Overview

Tropine丨120-29-6 is a bicyclic organic compound classified as a tropane alkaloid. It serves as an important intermediate in the synthesis of various pharmaceutical drugs, particularly those derived from tropane alkaloids like atropine and scopolamine.

02

Product Specifications

Property Specification
Appearance White or almost white crystalline
Melting Point 45.0℃ ~ 55.0℃
Water 1.0% max
Residue 0.1% max
Impurities β-Tropine: 0.15% max α-Tropinone: 0.5% max 6-β-Hydroxy Tropinone: 0.3% max Maximum Unknown Impurity: 0.15% max Total Impurities: 1.0% max
α-Tropine 99.0% min
Purity 98.0% ~ 101.0%
03

Applications

1. Pharmaceutical Industry

● Used as a key precursor in the synthesis of anticholinergic drugs, such as:
Atropine (used for dilating pupils and treating bradycardia)
Scopolamine (used for motion sickness and nausea)
Homatropine (used in ophthalmic applications)

● Plays a role in the development of neurological and gastrointestinal medications.

2. Chemical Synthesis

● Acts as a building block in the synthesis of more complex tropane derivatives.

● Used in the development of research chemicals and other biologically active molecules.

3. Biological and Pharmacological Research

● Studied for its effects on the nervous system due to its structural relation to cholinergic receptor modulators.

● Used in drug discovery and pharmacokinetic studies.

04

Benefits

✅ Essential Precursor for Tropane Alkaloids

● Serves as a starting material for important drugs with anticholinergic and antispasmodic properties.

✅ Versatile in Drug Development

● Supports the production of ophthalmic, gastrointestinal, and neurological medications.

✅ Valuable in Chemical Research

● Helps in synthesizing new bioactive compounds for potential therapeutic applications.

05

Conclusion

Tropine丨120-29-6 is a crucial intermediate in the synthesis of pharmaceutical compounds, particularly anticholinergic drugs like atropine and scopolamine. Its applications in medicine, chemical synthesis, and research highlight its importance in the pharmaceutical and scientific industries.

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