CAS · 24964-76-9
Product Overview
Triethyl orthobutyrate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Colorless liquid |
|---|---|
| Purity: | 99.0% min |
| Water: | 0.05% max |
Applications
Triethyl orthobutyrate is a versatile organic ester used primarily as a reagent and intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. It serves as a source of butyrate functionality in various condensation, transesterification, and esterification reactions, enabling the synthesis of carboxylic acid derivatives, heterocycles, and bioactive molecules. In medicinal chemistry, it is employed in the preparation of active pharmaceutical intermediates, prodrugs, and other functionalized compounds. Additionally, it finds applications in organic synthesis for the production of flavor and fragrance compounds, specialty chemicals, and as a reagent for chemical research involving alkylation and esterification reactions.
Benefits
The benefits of triethyl orthobutyrate stem from its high reactivity, chemical stability, and ease of handling. The orthobutyrate structure allows for controlled release of butyrate groups under acidic or basic conditions, facilitating selective transformations in multi-step syntheses. Its ester functionality provides versatility for conversion into acids, amides, or other derivatives, supporting efficient synthetic routes. The compound is soluble in common organic solvents, stable under normal laboratory conditions, and can be used in large-scale industrial synthesis, ensuring reproducible reactions and high yields.
Conclusion
Triethyl orthobutyrate is a valuable ester intermediate with broad applications in pharmaceuticals, fine chemicals, and organic synthesis. Its orthobutyrate and ester functionalities enable versatile chemical transformations, efficient derivatization, and the synthesis of bioactive molecules and specialty chemicals. By providing controlled reactivity and reproducibility, it continues to play an important role in chemical research, industrial synthesis, and pharmaceutical development.
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