CAS · 13492-01-8
Product Overview
Tranylcypromine Sulfate is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White to off-white powder |
|---|---|
| Identification (H NMR) | Consistent with the structure |
| Purity (HPLC, % area/area) | 98% min |
| cis-isomer (% area/area) | 0.5% max |
| Other individual impurity (% area/area) | 0.5% max |
| Loss on drying | 0.5% max |
Applications
Tranylcypromine sulfate (CAS 13492-01-8) is a pharmaceutical compound primarily used as a monoamine oxidase inhibitor (MAOI) in the treatment of major depressive disorder and other mood disorders. It works by inhibiting monoamine oxidase enzymes, thereby increasing the levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. Tranylcypromine sulfate is employed in clinical formulations for oral administration and is also used in research to study neuropharmacology, depression mechanisms, and enzyme inhibition kinetics. Additionally, it serves as a reference compound in drug development for the design of new MAOI derivatives and CNS-active agents.
Benefits
The benefits of tranylcypromine sulfate are derived from its potent and selective inhibition of monoamine oxidase, leading to effective antidepressant activity. Its sulfate salt form improves solubility, stability, and bioavailability, ensuring consistent therapeutic dosing. Compared to other MAOIs, it exhibits rapid onset of action and reliable pharmacokinetic properties. The compound also provides a valuable tool in research due to its well-characterized mechanism, facilitating studies on neurotransmitter regulation, neuroprotection, and psychiatric disorder models. Its clinical efficacy in treatment-resistant depression underscores its therapeutic importance.
Conclusion
In summary, tranylcypromine sulfate is a clinically significant MAOI used in the treatment of depression and mood disorders. Its applications include pharmaceutical formulations, neuropharmacological research, and MAOI reference studies, while its benefits lie in potent enzyme inhibition, improved solubility and bioavailability, and reliable therapeutic efficacy. With these properties, it remains an essential compound in both clinical practice and CNS-related research.
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