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Product Line: Cosmetic Chemicals

Tetrahexyldecyl ascorbate

CAS 183476-82-6

Molecular structure of Tetrahexyldecyl ascorbate

CAS · 183476-82-6

01

Product Overview

Tetrahexyldecyl ascorbate is a high-purity cosmetic-ingredients supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Character: Colorless to light yellow liquid
Purity: 98.0% min
Odor & Taste: A faint characteristic odor
IR: Should be consistent with that of the reference product
HPLC: The retention time of the main peak of the test solution should be the same as that of the control solution
Loss on Drying: 0.5% max
Water content: 0.1% max
Scorch residue: 0.1% max
Color (APHA): 100 max
Density (20℃): 0.930–0.943
Refractive index (25℃): 1.459–1.465
Pb: 10 ppm max
As: 2 ppm max
Hg: 1 ppm max
Cd: 5 ppm max
Total bacterial: 200 cfu/g max
Molds and Yeast Count: 100 cfu/g max
Thermotolerant Coliforms: Negative
Staphylococcus aureus: Negative
P. Aeruginosa: Negative
03

Applications

1. Cosmetic and Skincare Industry

a. Anti-Aging Products:

Tetrahexyldecyl ascorbate is widely used in anti-aging creams, serums, and lotions for its ability to:

● Stimulate collagen synthesis

● Reduce the appearance of fine lines and wrinkles

● Improve skin elasticity and firmness

It promotes collagen Types I and III, supporting skin structural integrity and youthfulness.

b. Skin Brightening and Tone Correction:

It is highly effective in reducing hyperpigmentation, melasma, and age spots by:

● Inhibiting tyrosinase activity, the enzyme responsible for melanin production

● Promoting a more even skin tone

● Lightening existing dark spots

c. Antioxidant Protection:

As a derivative of Vitamin C, it provides potent antioxidant protection against free radicals caused by:

● UV radiation

● Pollution

● Stress and aging

This helps prevent premature skin aging and photodamage.

2. Dermatological and Therapeutic Use

a. Treatment of Photodamage and UV-Induced Aging:

Tetrahexyldecyl ascorbate丨CAS 183476-82-6 is used in therapeutic creams to reduce UV-induced oxidative stress. Unlike water-soluble Vitamin C, this compound penetrates more deeply into the skin's lipid layers, making it more effective in:

● Treating sun-damaged skin

● Reducing inflammation

● Supporting skin barrier function

b. Adjunct in Acne and Rosacea Therapy:

Thanks to its anti-inflammatory and skin-soothing properties, it can be included in products designed to calm irritated or inflamed skin, especially when combined with niacinamide or retinoids.

3. Pharmaceutical and Cosmeceutical Formulations

a. Enhanced Formulation Stability:

Tetrahexyldecyl ascorbate is much more stable than L-ascorbic acid, which oxidizes rapidly in aqueous environments. Its lipophilicity allows:

● Long shelf life in oil-based or anhydrous formulations

● Compatibility with emulsions, serums, and creams

● Use at low concentrations (0.5%–2%) with strong activity

b. Improved Skin Penetration:

Its lipophilic structure enables deeper skin absorption through the stratum corneum, reaching the dermis more effectively than hydrophilic Vitamin C forms. This facilitates greater bioavailability and efficacy.

04

Benefits

1. Superior Stability and Shelf Life

Compared to ascorbic acid and other derivatives (e.g., sodium ascorbyl phosphate), tetrahexyldecyl ascorbate resists oxidation, heat, and light, making it ideal for commercial skincare formulations.

2. Deep Skin Penetration

Being lipid-soluble, it can pass through the skin's outer barrier and deliver Vitamin C benefits to the deeper layers of the skin-enhancing its collagen-boosting and antioxidant actions.

3. Multifunctional Skin Benefits

It delivers multiple dermatological benefits in a single ingredient, including:

● Brightening

● Anti-aging

● Antioxidant defense

● Anti-inflammatory action

4. Ideal for Sensitive or Dry Skin

Unlike acidic L-ascorbic acid, which can be irritating at high concentrations, tetrahexyldecyl ascorbate is gentler, making it suitable for:

● Sensitive skin

● Post-treatment skin (e.g., after chemical peels)

● Chronic conditions like eczema or rosacea

5. Synergistic with Other Actives

It can be effectively combined with:

● Retinol or peptides (for anti-aging)

● Niacinamide (for brightening and barrier repair)

● Ferulic acid (for photoprotection)

● Sunscreens (to boost UV protection)

05

Conclusion

Tetrahexyldecyl ascorbate丨CAS 183476-82-6 is a highly stable, oil-soluble Vitamin C derivative widely used in cosmetic, cosmeceutical, and dermatological formulations. It delivers the full spectrum of Vitamin C benefits-antioxidant protection, collagen synthesis, skin brightening-while offering superior skin penetration and reduced irritation. Its unique chemical properties make it an essential active ingredient in modern skincare products, especially for long-term use and in sensitive skin treatments.

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