CAS · 68399-81-5
Product Overview
TAPSO is a high-purity biological-buffer supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White crystalline powder |
|---|---|
| Assay | 99.0% to 101.0% |
| Water Content | 0.5% max |
| Loss on drying | 1% max |
| Melting point | 224 to 229°C |
| Solubility (1.0M aqueous) | Colorless, clear |
| pH (1.0M aqueous) | 7.0 to 8.0 |
| Heavy metal (Pb) | 0.0005% max |
| Ultraviolet absorbance / 260nm | 0.05 max |
| Ultraviolet absorbance / 280nm | 0.03 max |
Applications
1. Biological and Biochemical Research
TAPSO is a Good's buffer, specifically developed to maintain stable pH in biological and enzymatic systems.
Commonly used in:
Enzyme activity studies
Protein crystallization and purification
Molecular biology (e.g., PCR, electrophoresis)
Cell-free systems where CO₂-independent buffering is needed
2. Electrophoresis
Used in PAGE (polyacrylamide gel electrophoresis) for DNA, RNA, and protein separation where buffering between pH 7.0 and 8.2 is optimal.
3. Pharmaceutical and Diagnostic Formulations
Included in drug delivery systems and in vitro diagnostic reagents, especially where neutral to slightly basic pH is required and biocompatibility is essential.
4. Cell Culture Media
Supports pH regulation in mammalian or microbial culture when CO₂ buffering systems are not ideal or unavailable.
Benefits
1. Ideal Buffering Near Physiological pH
Excellent for experiments requiring neutral to mildly alkaline conditions, including most enzyme and cell-based studies.
2. Low Interaction with Metal Ions
Minimal chelation of divalent cations such as Mg²⁺, Ca²⁺, making it compatible with metal-dependent enzymes and cofactors.
3. Low UV Absorbance
Does not interfere with UV-based analytical techniques, including spectrophotometric assays of nucleic acids and proteins.
4. Biocompatible and Stable
Non-toxic, non-volatile, and stable in aqueous solution over time-ideal for long-term experiments or reagent kits.
5. High Solubility
Easily dissolves in water, enabling rapid preparation of buffers with reproducible pH performance.
Conclusion
TAPSO (CAS 68399-81-5) is a reliable and high-performance biological buffer ideal for maintaining near-neutral pH conditions in research, diagnostics, and pharmaceutical applications. With strong chemical stability, low metal ion binding, and high biocompatibility, TAPSO supports precise and reproducible results in a wide range of biochemical, molecular biology, and pharmaceutical processes.
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