CAS · 144-74-1
Product Overview
Sulfathiazole sodium丨144-74-1 is a sulfonamide antibiotic used in the treatment of bacterial infections. It is a sodium salt of sulfathiazole, which is itself a member of the sulfonamide class of drugs. Sulfonamides were among the first synthetic antibiotics and continue to be used in various medical and veterinary applications.
Product Specifications
| Property | Specification |
|---|---|
| Description | White to yellowish crystalline grain or powder |
| Purity (HPLC) | 99% min |
| Identification A (IR spectrometry) | Should correspond to the spectrum of a standard sulfathiazole sample in the range from 2000 cm-1 to 400 cm-1 |
| Identification B (Qualitative reaction) | Gives a characteristic reaction to primary aromatic amines |
| Identification C (Qualitative reaction) | Gives a characteristic reaction B to sodium |
| Loss on drying | 6~9% |
| Water solubility (25°C) | 5g/10mL min |
| Solution transparency | 5% aqueous solution of the drug should be transparent |
| pH (1% water solution) | 9.0~10.0 |
| Sulfonamide | 0.5% max |
| Amount of impurities | 2% max |
| Particle size | Should pass 20 mesh sieve (≤1mm) |
Applications
Detailed application notes for this product are available on request. Contact our technical team for the full application dossier, formulation guidance and regulatory documentation.
Benefits
Broad-Spectrum Activity:
Sulfathiazole sodium is effective against a wide variety of bacteria, making it useful in treating infections caused by both Gram-positive and Gram-negative pathogens. This broad-spectrum activity helps in treating infections where the causative bacteria may not be immediately known.
Cost-Effective:
Compared to many newer antibiotics, sulfathiazole sodium is relatively inexpensive, making it an affordable option in both human and veterinary medicine. This can be particularly important in resource-limited settings where access to newer antibiotics might be restricted.
Topical Use:
The drug's use in topical applications makes it useful in treating localized skin infections and wounds, where systemic antibiotics may not be necessary or desirable. It helps reduce the risk of wound infection and promotes healing.
Established Safety Profile:
Sulfathiazole sodium has been used for many decades and has an established safety profile when used appropriately. The drug has a history of low toxicity compared to some other antibiotics, particularly when used topically or in lower doses for infections.
Conclusion
Sulfathiazole sodium丨144-74-1 is a sulfonamide antibiotic with broad-spectrum activity against a wide range of bacterial infections. It is used in both human and veterinary medicine to treat infections of the respiratory tract, urinary tract, and skin. Its topical and systemic applications make it a versatile option for infection control. Despite its benefits, the drug is associated with the potential for allergic reactions, gastrointestinal issues, and blood-related side effects. Resistance to the drug may develop over time, limiting its long-term efficacy. Proper use, appropriate dosing, and monitoring of side effects are essential to maximizing its benefits and minimizing risks.
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