CAS · 100-79-8
Product Overview
Solketal is a high-purity food-additives supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless transparent liquid |
|---|---|
| Solketa (GC) | 99% min. |
| Water | 0.5% max. |
| Odour | odourless |
| Acid number | 0.20 mgKOH/g max. |
| Chromaticity | 10 Hazen max. |
| Acetone (GC) | 0.2% max. |
| Glycerinum (GC) | 0.3% max. |
Applications
Solketal is primarily used in chemical synthesis, pharmaceuticals, and specialty materials as a versatile protected diol and building block. In organic synthesis, it serves as a ketal-protected glycerol derivative, allowing selective functionalization of the molecule while protecting hydroxyl groups during multi-step reactions. In pharmaceutical and medicinal chemistry, Solketal is applied in the synthesis of prodrugs, intermediates, and bioactive molecules where controlled reactivity of hydroxyl groups is required. It is also used in polymer chemistry and materials science to prepare glycerol-based monomers, plasticizers, and specialty resins with improved solubility, stability, and hydrophobicity. Additionally, Solketal is employed in research to study protection/deprotection strategies, stereoselective reactions, and derivatization of polyols.
Benefits
Solketal offers several advantages that enhance its utility in chemical and pharmaceutical applications. Its ketal-protected hydroxyl groups provide chemical stability under a range of reaction conditions, enabling selective reactions without unwanted side reactions. The compound's solubility in organic solvents allows easy incorporation into various reaction systems and formulations. Upon deprotection, Solketal releases glycerol or other functional diols in a controlled manner, providing flexibility for downstream reactions and synthesis. Its well-defined structure, stability, and reactivity make it a reliable intermediate for multi-step syntheses, supporting efficient production of pharmaceuticals, polymers, and specialty chemicals.
Conclusion
Solketal is a versatile ketal-protected glycerol derivative used in chemical synthesis, pharmaceuticals, and materials science. Its protection of hydroxyl groups, stability, and controlled reactivity make it an effective intermediate for complex organic reactions and functionalized molecule development. Overall, Solketal supports selective synthesis, process efficiency, and the creation of advanced chemical and polymeric products.
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