Sodium nitrite N-15

Sodium nitrite N-15 is a high-purity analytical-reagents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

Sodium nitrite N‑15 is an isotopically labeled form of sodium nitrite in which the nitrogen atom is enriched with the N‑15 isotope. It is primarily used as a tracer and labeling reagent in chemical, biochemical, and analytical research. Its isotopic enrichment allows precise monitoring of nitrogen incorporation, transformation, and metabolism in organic and biological systems. In organic synthesis, it is used to study reaction mechanisms involving nitrosation, diazotization, and other nitrogen-transfer processes. In biochemical research, sodium nitrite N‑15 is applied to investigate nitrogen metabolism, enzymatic pathways, and nitric oxide production in cells, tissues, and microorganisms. The compound is also valuable in mass spectrometry, nuclear magnetic resonance (NMR), and isotope-ratio studies, where the N‑15 label enables accurate detection, quantification, and mechanistic analysis. Its unique isotopic signature supports the development of diagnostic assays, metabolic studies, and the design of isotopically labeled compounds for research and pharmaceutical applications.

The key benefits of sodium nitrite N‑15 lie in its isotopic labeling, high purity, and reliability for mechanistic and analytical studies. The N‑15 enrichment allows unambiguous tracing of nitrogen atoms through complex chemical or biological transformations, providing insights into reaction pathways and metabolic fluxes that are difficult to obtain with unlabeled sodium nitrite. It is chemically identical to natural sodium nitrite, ensuring that its behavior in reactions or biological systems is representative, while its isotopic signature enables precise detection using NMR, mass spectrometry, or isotope-ratio monitoring. The compound is stable, water-soluble, and compatible with standard reaction and biological conditions, making it easy to handle in both laboratory and analytical workflows. Its use reduces experimental uncertainty and enhances reproducibility in studies requiring isotopic labeling.

Sodium nitrite N‑15 is a specialized isotopically labeled reagent used in chemical, biochemical, and analytical research. Its N‑15 enrichment enables precise tracing of nitrogen atoms in reactions and metabolic pathways, facilitating mechanistic studies, isotope-ratio analysis, and the development of diagnostic or research assays. By combining chemical equivalence to natural sodium nitrite with the unique advantages of isotopic labeling, it provides a reliable, stable, and versatile tool for studying nitrogen transfer, metabolism, and transformation in complex systems.

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