CAS · 38330-80-2
Product Overview
Potassium 3-methoxy-3-oxopropanoate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White crystalline powder |
|---|---|
| Assay | 98–102% |
| Melting point | 190–200°C |
| Loss on drying | 0.5% max |
Applications
Potassium 3-methoxy-3-oxopropanoate is mainly used as a synthetic intermediate in organic chemistry and pharmaceutical research. It functions as a potassium salt of a β-keto ester derivative, making it suitable for carbon–carbon bond-forming reactions, condensations, and nucleophilic additions. The compound is applied in the synthesis of heterocyclic compounds, active pharmaceutical ingredient intermediates, and fine chemicals that require controlled enolate chemistry. In research laboratories, it is used to explore reaction mechanisms involving stabilized carbanions, ester transformations, and substitution reactions. It is also incorporated into process development studies where salt forms are evaluated for improved solubility, reactivity, and handling during multi-step synthesis.
Benefits
The compound offers several benefits related to its salt form and reactive functionality. The potassium counterion enhances stability and allows convenient handling compared with neutral β-keto esters, while also improving solubility in polar solvents. Its structure enables predictable enolate formation, supporting high selectivity and reproducibility in synthetic reactions. The methoxy and oxo groups provide versatile points for further functionalization, allowing access to a wide range of derivatives. Its defined composition supports accurate dosing and consistent performance in laboratory and development-scale reactions. These characteristics make it a practical and reliable building block for complex organic synthesis.
Conclusion
Potassium 3-methoxy-3-oxopropanoate is a useful intermediate for constructing advanced organic molecules in pharmaceutical and fine chemical research. Its applications in carbon–carbon bond formation and heterocycle synthesis, together with benefits such as stability, solubility, and predictable reactivity, make it an effective tool in modern synthetic chemistry. The compound supports efficient multi-step synthesis and the development of diverse functionalized compounds.
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