CAS · 142-63-2
Product Overview
Piperazine hexahydrate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Item | Specification |
|---|---|
| Appearance | White to light yellow crystal |
| Purity (GC) | 98% min |
| Ignition residue | 0.01% max |
| Melting Point (MP) | 43~45°C |
| Boiling Point (BP) | 125-130°C |
Applications
1. Pharmaceutical Industry
● Anthelmintic Agent:
Piperazine hexahydrate丨CAS 142-63-2 is used to treat parasitic worm infections, especially roundworms (Ascaris lumbricoides) and pinworms (Enterobius vermicularis).
It works by paralyzing the worms, allowing them to be expelled from the intestines via natural peristalsis.
● Formulation Component:
Used as an intermediate in the synthesis of various pharmaceutical drugs, including antihistamines, antipsychotics, and antidepressants.
2. Chemical Synthesis
● Acts as a building block in organic synthesis for the preparation of:
Polymers
Resins
Pharmaceutical precursors
● Involved in the manufacture of piperazine derivatives, such as:
Piperazine citrate
Piperazine adipate
Other salts for medicinal use
3. Water Treatment
● Functions as a corrosion inhibitor in boiler water treatment systems due to its buffering capacity and metal ion complexation.
4. Polymer and Resin Industry
● Used in the production of epoxy curing agents and polyamide resins.
● Enhances flexibility and adhesion properties in coatings and adhesives.
5. Agricultural Chemicals
● Occasionally utilized in the formulation of veterinary anthelmintics.
● May serve as an intermediate in the production of agrochemicals.
6. Laboratory Use
● Used as a buffering agent or complexing agent in chemical reactions.
● Employed in metal ion complexation studies and pH stabilization.
Benefits
√ Effective Anthelmintic
● Piperazine is a safe and effective treatment for helminthic infections, particularly in pediatric populations.
● Has a low toxicity profile and minimal side effects when used properly.
√ Versatile Chemical Intermediate
● Its bifunctional amine structure makes it useful in the design of drugs, resins, and polymeric materials.
√ Hydrated Form Stability
● The hexahydrate form improves stability and handling, making it easier to store and dose in pharmaceutical formulations.
√ Non-Corrosive Nature
● In industrial water systems, its use helps reduce corrosion and extend the lifespan of equipment.
√ Water-Soluble and Reactive
● Easily dissolves in water, making it suitable for aqueous reactions, biological systems, and topical applications.
Conclusion
Piperazine hexahydrate丨CAS 142-63-2 is a multifunctional compound with wide-ranging applications in medicine, chemical synthesis, polymer manufacturing, and industrial water treatment. Its primary medical role as an anthelmintic has made it a staple in global healthcare, especially in developing countries. In industrial settings, it provides versatility and performance benefits in chemical formulations and corrosion protection systems.
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Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.