CAS · 7681-93-8
Product Overview
Pimaricin is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade | USP42 |
|---|---|
| Appearance | Off-white to cream-colored powder |
| Identification | UV absorption, complies |
| Crystallinity | Complies |
| pH | 5 to 7.5 |
| Water | 6% to 9% |
| Assay (on the anhydrous basis) | 90% to 102% |
| Methanol | 3000 ppm max |
| Ethanol | 5000 ppm max |
| Acetone | 5000 ppm max |
| DMSO | 5000 ppm max |
Applications
Pimaricin, also known as natamycin, is a polyene macrolide antibiotic widely used in pharmaceuticals, food preservation, and veterinary applications. In medicine, it is applied topically to treat fungal infections of the skin, eyes, and mucous membranes due to its potent antifungal activity against yeasts and molds. In the food industry, pimaricin is used as a natural preservative for dairy products, cheeses, and processed meats to inhibit the growth of spoilage fungi and extend shelf life. Additionally, it is employed in veterinary medicine for treating fungal infections in animals and in research for studying antifungal mechanisms and developing new antifungal agents. Its broad-spectrum activity and low toxicity make it suitable for both human and animal applications.
Benefits
The benefits of pimaricin derive from its strong antifungal efficacy, safety profile, and natural origin. It exhibits selective binding to fungal sterols, disrupting fungal cell membranes without significant toxicity to humans or animals. This selectivity makes it a preferred option for both medical and food applications. Pimaricin is effective at low concentrations, providing cost-efficient preservation and therapeutic solutions. Its stability under various storage conditions and compatibility with other ingredients in formulations enhance its versatility. Additionally, as a naturally derived compound, it aligns with regulatory preferences for safe, eco-friendly preservatives and pharmaceuticals.
Conclusion
In summary, pimaricin is a polyene macrolide with applications in pharmaceuticals, food preservation, veterinary medicine, and antifungal research. Its benefits include potent antifungal activity, selectivity, low toxicity, stability, and cost-effectiveness. By combining efficacy with safety and versatility, pimaricin remains a valuable compound in medical treatment, food protection, and research on antifungal therapies.
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