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N,N-Dimethylformamide

CAS 68-12-2

Molecular structure of N,N-Dimethylformamide

CAS · 68-12-2

01

Product Overview

N,N-Dimethylformamide is a high-purity solvents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

DMF (HPLC): 99.9% min
Methanol: 0.001% max
Moisture: 0.05% max
Chrominance (PT-CO): 5 max
Alkalinity (Dimethylamine): 0.001% max
Acidity (Formic acid): 0.001% max
pH (25℃, 20% aqueous solution): 6.5 to 8
Electric conductivity: 2 µS/cm max
Fe: 0.05 mg/kg max
03

Applications

1. Industrial Solvent

N,N-Dimethylformamide丨CAS 68-12-2 is a powerful polar aprotic solvent, making it extremely valuable in a wide range of industries:

● Polymer Industry:
Used in the production and processing of polyacrylonitrile, polyurethane, and PVC
Solvent for spinning fibers and films

● Pharmaceutical Manufacturing:
Solvent for active pharmaceutical ingredient (API) synthesis
Ideal for peptide coupling reactions and heterocyclic compound formation

● Electronics & Semiconductor Industry:
Cleaning and degreasing agent for electronics
Solvent for photoresist materials and circuit board fabrication

2. Organic Synthesis

● Widely used as a reaction medium due to its ability to dissolve a wide range of compounds

● Supports reactions such as:
Nucleophilic substitutions
Coupling reactions (e.g., Suzuki, Heck, Sonogashira)
Grignard and lithiation reactions
Formylation and acylation

3. Analytical and Research Applications

● Used in chromatographic analysis, especially in HPLC and spectroscopy

● Solvent for spectrophotometric measurements and sample preparation

4. Agrochemical and Dye Manufacturing

● Solvent and intermediate in the production of insecticides, fungicides, and herbicides

● Used in the synthesis of azo dyes, reactive dyes, and pigments

04

Benefits

√ Excellent Solvent Power

Dissolves both polar and non-polar compounds, enabling versatile use across many chemical processes

√ High Boiling Point

Stable at high reaction temperatures, making it suitable for thermal reactions

√ Low Viscosity

Facilitates smooth material handling and rapid diffusion in reaction media

√ Compatibility

Mixes with water, alcohols, ethers, esters, and hydrocarbons-ideal for multi-component systems

Conclusion

N,N-Dimethylformamide丨CAS 68-12-2 is a cornerstone chemical in industrial and laboratory applications due to its exceptional solvent properties, chemical stability, and broad compatibility. Despite its toxicological concerns, its role in pharmaceuticals, polymer processing, electronics, and chemical synthesis makes it an indispensable solvent in modern chemical industries. Proper handling and safety protocols ensure its benefits are maximized while minimizing risks.

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05

Conclusion

A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.