CAS · 3891-07-4
Product Overview
N-Hydroxyethylphthalimide is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to off-white crystal powder |
|---|---|
| Purity: | 99% min |
| MP: | 126-129℃ |
| Water: | 0.5% max |
| Residue on ignition: | 0.1% max |
| Heavy metal: | 10 ppm max |
Applications
1. Organic Synthesis Intermediate
Used as a building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.
The hydroxyethyl group provides a handle for further functionalization, such as etherification, esterification, or conjugation.
Phthalimide moiety can be utilized in Gabriel synthesis to prepare primary amines after appropriate modification.
2. Polymer Additives
Acts as a precursor to phthalimide-based stabilizers and antioxidants used in polymer industries.
Improves thermal stability and oxidation resistance of plastics like polyethylene and polypropylene.
3. Pharmaceuticals
Used in the design of prodrugs and bioactive molecules where phthalimide acts as a protective or modulating group.
The compound can serve as a scaffold for developing compounds with antimicrobial, anti-inflammatory, or anticancer activities.
4. Chemical Research
Employed in laboratory research for the synthesis of functionalized amines, hydroxylated compounds, and heterocycles.
Its bifunctional nature (phthalimide and hydroxyethyl) makes it a useful reagent for studying reaction mechanisms and developing new synthetic methodologies.
Benefits
✅ Versatile Functional Group
Combines the reactivity of the phthalimide ring and the hydroxyethyl side chain, enabling diverse chemical transformations.
✅ Stable and Easy to Handle
Solid crystalline form offers good shelf stability and ease of storage and handling.
✅ Facilitates Selective Reactions
The hydroxyethyl group can be selectively modified without disturbing the phthalimide core, offering synthetic flexibility.
✅ Widely Used Scaffold
The phthalimide structure is well-known and commonly used in pharmaceuticals, facilitating regulatory and development pathways.
Conclusion
N-Hydroxyethylphthalimide (CAS 3891-07-4) is a valuable chemical intermediate widely employed in organic synthesis, polymer stabilization, and pharmaceutical research. Its dual functional groups make it highly versatile for developing advanced materials and bioactive compounds, supporting innovation across multiple chemical industries.
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