CAS · 36421-15-5
Product Overview
N-(3-Chloropropyl)dibutylamine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless to light yellow liquid |
|---|---|
| Identification | GC |
| Purity (GC) | 97% min |
| 1-Bromo-chloropropane | 0.1% max |
| Dibutyl amine | 0.5% max |
| N1,N1,N3,N3-Tetrabutyl-1,3-propanediamine | 1.5% max |
| Water | 0.5% max |
| Assay (on dried basis, by titration) | 97% min |
Applications
N-(3-Chloropropyl)dibutylamine is primarily used as a chemical intermediate in the synthesis of quaternary ammonium salts, which are widely applied as disinfectants, fabric softeners, antistatic agents, and phase transfer catalysts. It also serves as a precursor for specialty surfactants used in industrial cleaning, personal care products, and emulsion polymerization processes. In pharmaceutical and fine chemical research, the compound can be used for the preparation of functionalized nitrogen-containing molecules, including intermediates in heterocyclic chemistry and organic synthesis. Additionally, it finds applications in materials science, where it can be incorporated into polymers or coatings to modify surface properties such as hydrophilicity, charge density, or antimicrobial activity.
Benefits
One of the key benefits of N-(3-Chloropropyl)dibutylamine is its high reactivity, which allows selective functionalization at the chloropropyl group while retaining the nucleophilic tertiary amine functionality. This dual reactivity enables efficient synthesis of a wide range of quaternary ammonium compounds and derivatives. The compound is liquid at room temperature, providing ease of handling, mixing, and incorporation into reaction systems. Its tertiary amine structure contributes to chemical stability under standard storage conditions, and it is compatible with many organic solvents used in industrial synthesis. From a manufacturing perspective, it enables high-yield reactions with minimal by-products, supporting efficient scale-up in chemical production. Additionally, its ability to form cationic intermediates is valuable for designing antimicrobial, surfactant, and functional polymer products.
Conclusion
N-(3-Chloropropyl)dibutylamine is a versatile tertiary amine intermediate widely used in the synthesis of quaternary ammonium compounds, surfactants, and functionalized chemical products. Its reactive chloropropyl group, nucleophilic amine functionality, and chemical stability make it a valuable building block in industrial, pharmaceutical, and materials chemistry. As demand grows for functional chemicals and specialty intermediates, this compound remains an important tool for modern chemical synthesis and product development.
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