CAS · 72432-03-2
Product Overview
Miglitol is a high-purity biochemical-reagents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White powder |
|---|---|
| Purity | 98% min |
| 1H NMR Spectrum | Conforms to structure |
| Optical rotation | -12.57° (C=0.56 H2O) |
| Structure | Conforms to structure |
Applications
Miglitol is an oral antihyperglycemic agent used in the management of type 2 diabetes mellitus. It functions as an α-glucosidase inhibitor, delaying the digestion and absorption of carbohydrates in the small intestine, thereby reducing postprandial blood glucose levels. Miglitol is primarily prescribed as a therapeutic agent for patients with impaired glucose tolerance or diabetes, often in combination with diet control or other antidiabetic medications. In pharmaceutical research, it is also employed as a reference compound for studying carbohydrate metabolism, enzyme inhibition, and the development of new α-glucosidase inhibitors with improved efficacy and safety profiles.
Benefits
The key benefits of Miglitol lie in its ability to effectively control postprandial hyperglycemia without stimulating insulin secretion, minimizing the risk of hypoglycemia compared to other antidiabetic agents. Its oral administration makes it convenient for patients, and it demonstrates predictable pharmacokinetics and good tolerability. Additionally, Miglitol helps reduce glycemic spikes that contribute to long-term diabetic complications such as cardiovascular disease, neuropathy, and retinopathy. By targeting carbohydrate absorption, it complements other antidiabetic therapies and supports comprehensive blood glucose management.
Conclusion
Miglitol is a valuable therapeutic agent in the management of type 2 diabetes, offering effective postprandial blood glucose control with low risk of hypoglycemia. Its role as an α-glucosidase inhibitor provides a unique mechanism of action, making it useful both in clinical treatment and pharmaceutical research. By improving glycemic regulation and supporting combination therapy strategies, Miglitol contributes significantly to diabetes care and patient quality of life.
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